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Genetics|June 19, 2026
Genetic analysis of sensitivity to temperature fluctuations identifies acclimation stress as a novel type of cellular stress in Caenorhabditis elegansNoah Lilienfeldt, Yifan Tai, Han Sun, et al.Science Advances|November 30, 2022
Stimulation of RAS-dependent ROS signaling extends longevity by modulating a developmental program of global gene expressionRobyn Branicky, Ying Wang, Arman Khaki, et al.Plos Genetics|July 18, 2014
Muscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of duchenne muscular dystrophyAngeliki Chalkiadaki, Masaki Igarashi, Armiyaw Sebastian Nasamu, et al.Genes & Development|January 16, 2004
Calorie restriction extends yeast life span by lowering the level of NADHSu-Ju Lin, Ethan Ford, Marcia Haigis, et al.Plos One|September 23, 2017
SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosisKayvan Zainabadi, Cassie J Liu, Alison L M Caldwell, et al.Genes & Development|April 19, 2006
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcriptionEthan Ford, Renate Voit, Gregory Liszt, et al.Cell Reports|March 9, 2017
Mutations that Allow SIR2 Orthologs to Function in a NAD+-Depleted EnvironmentCaitlin R Ondracek, Vincent Frappier, Alison E Ringel, et al.Aging Cell|June 19, 2012
Deviation of innate circadian period from 24 h reduces longevity in miceSergiy Libert, Michael S Bonkowski, Kelli Pointer, et al.Genetics|April 13, 2010
Decreased energy metabolism extends life span in Caenorhabditis elegans without reducing oxidative damageJeremy Michael Van Raamsdonk, Yan Meng, Darius Camp, et al.Genetics|May 6, 2004
Saccharomyces cerevisiae SSD1-V confers longevity by a Sir2p-independent mechanismMatt Kaeberlein, Alex A Andalis, Gregory B Liszt, et al.Pageof 20