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Nature|July 19, 2002
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respirationSu-Ju Lin, Matt Kaeberlein, Alex A Andalis, et al.Nature|June 4, 2004
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gammaFrédéric Picard, Martin Kurtev, Namjin Chung, et al.Nature Genetics|July 6, 2004
Essential role of limiting telomeres in the pathogenesis of Werner syndromeSandy Chang, Asha S Multani, Noelia G Cabrera, et al.The Journal of Biological Chemistry|November 14, 2006
SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylationShinji Kume, Masakazu Haneda, Keizo Kanasaki, et al.American Journal of Physiology. Lung Cellular and Molecular Physiology|September 17, 2013
SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPDHongwei Yao, Jae-woong Hwang, Isaac K Sundar, et al.Gastroenterology|November 5, 2013
Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21Yu Li, Kimberly Wong, Amber Giles, et al.Nature Medicine|December 20, 2011
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathwayHyunkyung Jeong, Dena E Cohen, Libin Cui, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|February 16, 2011
Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liverYu Li, Shanqin Xu, Amber Giles, et al.Development (Cambridge, England)|August 22, 2014
SirT1 is required in the male germ cell for differentiation and fecundity in miceEric L Bell, Ippei Nagamori, Eric O Williams, et al.Aging Cell|June 28, 2024
Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairmentHolly E Holmes, Rafael E Valentin, Fredrik Jernerén, et al.Pageof 20