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Journal of Medicinal Chemistry|January 5, 2017
Difluoromethyl Bioisostere: Examining the "Lipophilic Hydrogen Bond Donor" ConceptYossi Zafrani, Dina Yeffet, Gali Sod-Moriah, et al.
International Journal of Pharmaceutics|August 29, 2025
Pillar[n]arenes versus cyclodextrins as supramolecular carriers for improved bioavailability: Idebenone as a model drugDina Yeffet, Boris Smolkin, Ishay Columbus, et al.
Journal of Tissue Engineering and Regenerative Medicine|November 22, 2021
Poly(vinyl alcohol)-methacrylate with CRGD peptide: A photocurable biocompatible hydrogelMichael Goldvaser, Eyal Epstein, Osnat Rosen, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|October 31, 2025
The impact of solid and liquid lipids and their lipolysis on griseofulvin bioavailability. In vitro dissolution, in vivo and ex vivo porcine model studySigal Saphier, Oljora Rezhdo, Guy Yaccov, et al.
European Journal of Medicinal Chemistry|September 17, 2025
Intramolecular hydrogen-bonding motifs in the 14-oxymorphinan opioids: An experimental and computational studyDina Yeffet, Ishay Columbus, Naama Lifshin-Karton, et al.
Journal of Medicinal Chemistry|April 12, 2021
Modulation of the H-Bond Basicity of Functional Groups by α-Fluorine-Containing Functions and its Implications for Lipophilicity and BioisosterismYossi Zafrani, Galit Parvari, Dafna Amir, et al.
Journal of Medicinal Chemistry|May 16, 2019
CF<sub>2</sub>H, a Functional Group-Dependent Hydrogen-Bond Donor: Is It a More or Less Lipophilic Bioisostere of OH, SH, and CH<sub>3</sub>?Yossi Zafrani, Gali Sod-Moriah, Dina Yeffet, et al.
Journal of Medicinal Chemistry|February 12, 2026
From NH<sup>+</sup> Chemical Shifts to Chemical Insights: A <sup>1</sup>H NMR Spectroscopic Window into Amine p<i>K</i><sub>a</sub>, Anion p<i>K</i><sub>BHX,</sub> and Charge-Assisted Intramolecular H-Bond Assessment from a Medicinal Chemistry PerspectiveShlomi Elias, Dafna Amir, Boris Smolkin, et al.
Communications Chemistry|September 15, 2023
Species-specific lipophilicities of fluorinated diketones in complex equilibria systems and their potential as multifaceted reversible covalent warheadsIshay Columbus, Lee Ghindes-Azaria, Ido Michael Herzog, et al.
Journal of Medicinal Chemistry|July 16, 2024
Addressing the Opioids Lipophilicity Challenge via a Straightforward and Simultaneous <sup>1</sup>H NMR-Based log<i>P</i>/<i>D</i> Determination, Both Separately and in MixturesDina Yeffet, Ishay Columbus, Galit Parvari, et al.
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