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The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|July 11, 2014
Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like modelsDora Games, Elvira Valera, Brian Spencer, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 30, 2021
Wild-type GBA1 increases the α-synuclein tetramer-monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in miceKelly E Glajch, Tim E Moors, Yi Chen, et al.
Human Molecular Genetics|September 16, 2017
Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cellsUlf Dettmer, Nagendran Ramalingam, Victoria E von Saucken, et al.
Annals of Neurology|May 4, 2010
First appraisal of brain pathology owing to A30P mutant alpha-synucleinKay Seidel, Ludger Schöls, Silke Nuber, et al.
Human Molecular Genetics|November 26, 2015
Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2Nicolas Casadei, Poonam Sood, Thomas Ulrich, et al.
Human Molecular Genetics|March 13, 2014
Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic miceMeike Diepenbroek, Nicolas Casadei, Hakan Esmer, et al.
Neurogenetics|September 18, 2009
Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in miceSilke Nuber, Thomas Franck, Hartwig Wolburg, et al.
Annals of Neurology|September 30, 2020
A Stearoyl-Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α-Synuclein MiceSilke Nuber, Alice Y Nam, Molly M Rajsombath, et al.
Brain : a Journal of Neurology|March 26, 2014
Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivoEdward Rockenstein, Silke Nuber, Cassia R Overk, et al.
Plos One|July 15, 2010
A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old miceAlexander Kurz, Kay L Double, Isabel Lastres-Becker, et al.
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