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Frontiers in Cell and Developmental Biology|February 9, 2023
Spermine oxidase induces DNA damage and sensitizes fusion negative rhabdomyosarcoma cells to irradiationClara Perrone, Silvia Pomella, Matteo Cassandri, et al.Cancer Letters|July 21, 2019
Pro-differentiating and radiosensitizing effects of inhibiting HDACs by PXD-101 (Belinostat) in in vitro and in vivo models of human rhabdomyosarcoma cell linesFrancesco Marampon, Valentina Di Nisio, Ilaria Pietrantoni, et al.Cells|September 23, 2022
Hyperactive Akt1 Signaling Increases Tumor Progression and DNA Repair in Embryonal Rhabdomyosarcoma RD Line and Confers Susceptibility to Glycolysis and Mevalonate Pathway InhibitorsSilvia Codenotti, Daniela Zizioli, Luca Mignani, et al.International Journal of Radiation Biology|May 12, 2021
Romidepsin (FK228) fails in counteracting the transformed phenotype of rhabdomyosarcoma cells but efficiently radiosensitizes, in vitro and in vivo, the alveolar phenotype subtypeAlessandra Rossetti, Francesco Petragnano, Luisa Milazzo, et al.International Journal of Radiation Biology|March 10, 2020
Modulating the dose-rate differently affects the responsiveness of human epithelial prostate- and mesenchymal rhabdomyosarcoma-cancer cell line to radiationFrancesco Petragnano, Ilaria Pietrantoni, Valentina Di Nisio, et al.Frontiers in Pharmacology|December 19, 2022
The botanical drug PBI-05204, a supercritical CO<sub>2</sub> extract of <i>Nerium oleander</i>, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy <i>in vitro</i> and <i>in vivo</i>Sara Vaccaro, Alessandra Rossetti, Antonella Porrazzo, et al.Cell Death Discovery|November 3, 2025
Neddylation inhibition induces DNA double-strand breaks, hampering tumor growth in vivo, and promotes radiosensitivity in PAX3-FOXO1 rhabdomyosarcomaFrancesca Antonella Aiello, Lucrezia D'Archivio, Marika Attili, et al.Cell Death & Disease|June 1, 2026
Multi-omics analyses identify EZH2 as a central driver in rhabdomyosarcoma radioresistance and highlight Tazemetostat as an effective radiosensitizer in vitro and in vivoMatteo Cassandri, Antonella Porrazzo, Simona Camero, et al.Journal of Biomedical Science|August 29, 2020
Clinically relevant radioresistant rhabdomyosarcoma cell lines: functional, molecular and immune-related characterizationFrancesco Petragnano, Ilaria Pietrantoni, Simona Camero, et al.Cell Death Discovery|August 6, 2024
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaksMatteo Cassandri, Antonella Porrazzo, Silvia Pomella, et al.Pageof 4