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Molecules (Basel, Switzerland)|December 2, 2017
In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage AntimalarialNicoletta Basilico, Silvia Parapini, Anna Sparatore, et al.ACS Infectious Diseases|May 8, 2024
Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic AgentsAlexandra Ioana Corfu, Nuno Santarem, Sara Luelmo, et al.RSC Chemical Biology|January 5, 2024
Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in <i>Plasmodium falciparum</i>Monika Lisauskaitė, Gemma L Nixon, Christopher M Woodley, et al.Journal of Medicinal Chemistry|February 19, 2008
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agentsCaterina Fattorusso, Giuseppe Campiani, Gagan Kukreja, et al.European Journal of Medicinal Chemistry|January 3, 2025
Novel antimalarial 3-substituted quinolones isosteres with improved pharmacokinetic propertiesSiyuan Ge, Rongchao Jian, Qiwei Xuan, et al.European Journal of Medicinal Chemistry|March 24, 2018
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analoguesAlessandra Vallone, Sarah D'Alessandro, Simone Brogi, et al.Journal of Medicinal Chemistry|February 19, 2008
Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studiesSandra Gemma, Giuseppe Campiani, Stefania Butini, et al.Journal of Medicinal Chemistry|December 31, 2008
Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarialsSandra Gemma, Giuseppe Campiani, Stefania Butini, et al.Journal of Medicinal Chemistry|July 13, 2012
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profilingSandra Gemma, Caterina Camodeca, Salvatore Sanna Coccone, et al.Journal of Medicinal Chemistry|March 17, 2009
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquinePaul M O'Neill, Alison E Shone, Deborah Stanford, et al.Pageof 12