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Neuropharmacology|September 23, 2014
Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: a comparison with carbamazepine, oxcarbazepine and lacosamideSimon Hebeisen, Nuno Pires, Ana I Loureiro, et al.
Planta Medica|July 16, 2016
Caco-2 Permeability Studies and In Vitro hERG Liability Assessment of Tryptanthrin and IndolinoneEvelyn A Jähne, Daniela E Eigenmann, Fahimeh Moradi-Afrapoli, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|July 8, 2024
Deconvoluting and derisking QRS complex widening to improve cardiac safety profile of novel plasmepsin X antimalarialsAnnie Delaunois, Alvaro Cardenas, Teresa de Haro, et al.
Pharmacology Research & Perspectives|February 7, 2023
Testing the nonclinical Comprehensive In Vitro Proarrhythmia Assay (CiPA) paradigm with an established anti-seizure medication: Levetiracetam case studyAnnie Delaunois, François-Xavier Mathy, Miranda Cornet, et al.
Journal of Pharmacological and Toxicological Methods|May 25, 2020
Unraveling the mechanism and the risk behind seizure liability of lead compounds in a neuroscience projectAnnie Delaunois, Michael V Accardi, Véronique André, et al.
Clinical and Translational Science|February 23, 2021
Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off-label in the first wave of COVID-19Annie Delaunois, Matthew Abernathy, Warren D Anderson, et al.
Scientific Reports|March 30, 2020
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cellsJames Kramer, Herbert M Himmel, Anders Lindqvist, et al.
Scientific Reports|July 16, 2020
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cellsJames Kramer, Herbert M Himmel, Anders Lindqvist, et al.
Nature Genetics|March 4, 2003
Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsiesKarsten Haug, Maike Warnstedt, Alexi K Alekov, et al.
Scientific Reports|August 16, 2025
Multi-laboratory comparisons of manual patch clamp hERG data generated using standardized protocols and following ICH S7B Q&A 2.1 best practicesClaudia Alvarez Baron, Jun Zhao, Huimei Yu, et al.
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