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Simon J Cook

Showing results (71-80 of 100) with videos related to

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Journal of Cell Science|March 8, 2011
BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylationCeri M Wiggins, Peter Tsvetkov, Mark Johnson, et al.
The EMBO Journal|May 26, 2007
ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xLKatherine E Ewings, Kathryn Hadfield-Moorhouse, Ceri M Wiggins, et al.
Ebiomedicine|July 3, 2015
DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down SyndromeSònia Najas, Juan Arranz, Pamela A Lochhead, et al.
Molecular Cancer Therapeutics|November 22, 2019
Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2Andrew M Kidger, Joanne M Munck, Harpreet K Saini, et al.
Blood|December 14, 2011
Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemiaAlex Paterson, C Ian Mockridge, Jemimah E Adams, et al.
Journal of Cell Science|December 24, 2013
Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translationClaire L Cope, Rebecca Gilley, Kathryn Balmanno, et al.
Oncogene|February 26, 2004
ERK1/2 and p38 cooperate to induce a p21CIP1-dependent G1 cell cycle arrestDaniel E Todd, Ruth M Densham, Sarah A Molton, et al.
EMBO Reports|November 20, 2025
FOXO1 links KRAS G12D and G12V alleles to glutamine and nitrogen metabolism in colorectal cancerSuzan Ber, Ming Yang, Marco Sciacovelli, et al.
Science Signaling|June 17, 2011
A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P. A. W. Edwards, P. D. Smith, S. J. CookAnnette S Little, Kathryn Balmanno, Matthew J Sale, et al.
Molecular Cell|November 18, 2019
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during MitosisRichard I Odle, Simon A Walker, David Oxley, et al.
Pageof 10

Showing results (71-80 of 100) with videos related to

Sort By:
Pageof 10
Journal of Cell Science|March 8, 2011
BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylationCeri M Wiggins, Peter Tsvetkov, Mark Johnson, et al.
The EMBO Journal|May 26, 2007
ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xLKatherine E Ewings, Kathryn Hadfield-Moorhouse, Ceri M Wiggins, et al.
Ebiomedicine|July 3, 2015
DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down SyndromeSònia Najas, Juan Arranz, Pamela A Lochhead, et al.
Molecular Cancer Therapeutics|November 22, 2019
Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2Andrew M Kidger, Joanne M Munck, Harpreet K Saini, et al.
Blood|December 14, 2011
Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemiaAlex Paterson, C Ian Mockridge, Jemimah E Adams, et al.
Journal of Cell Science|December 24, 2013
Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translationClaire L Cope, Rebecca Gilley, Kathryn Balmanno, et al.
Oncogene|February 26, 2004
ERK1/2 and p38 cooperate to induce a p21CIP1-dependent G1 cell cycle arrestDaniel E Todd, Ruth M Densham, Sarah A Molton, et al.
EMBO Reports|November 20, 2025
FOXO1 links KRAS G12D and G12V alleles to glutamine and nitrogen metabolism in colorectal cancerSuzan Ber, Ming Yang, Marco Sciacovelli, et al.
Science Signaling|June 17, 2011
A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P. A. W. Edwards, P. D. Smith, S. J. CookAnnette S Little, Kathryn Balmanno, Matthew J Sale, et al.
Molecular Cell|November 18, 2019
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during MitosisRichard I Odle, Simon A Walker, David Oxley, et al.
Pageof 10