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Journal of Medicinal Chemistry|December 4, 2008
In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivativesSimon Lucas, Ralf Heim, Christina Ries, et al.Journal of Natural Products|December 30, 2010
Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavataAnne F Barslund, Mette H Poulsen, Tinna B Bach, et al.European Heart Journal. Case Reports|June 18, 2026
Rifampicin for the treatment of a cardiogenic shock related to mavacamten toxicity: the worse and the best of drug interactions from a case reportSimon Lucas, Benjamin Hennart, Pascal de Groote, et al.European Journal of Medicinal Chemistry|November 2, 2018
Discovery of a subnanomolar and selective spirocyclic agonist of the glucocorticoid receptorEduard Badarau, Frédéric Robert, Stéphane Massip, et al.Journal of Medicinal Chemistry|October 25, 2012
General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptorsSimon Lucas, Mette H Poulsen, Niels G Nørager, et al.Journal of Medicinal Chemistry|September 4, 2008
Novel aldosterone synthase inhibitors with extended carbocyclic skeleton by a combined ligand-based and structure-based drug design approachSimon Lucas, Ralf Heim, Matthias Negri, et al.Journal of Medicinal Chemistry|January 17, 2013
Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptorsMette H Poulsen, Simon Lucas, Tinna B Bach, et al.Journal of Medicinal Chemistry|August 5, 2008
Overcoming undesirable CYP1A2 inhibition of pyridylnaphthalene-type aldosterone synthase inhibitors: influence of heteroaryl derivatization on potency and selectivityRalf Heim, Simon Lucas, Cornelia M Grombein, et al.Journal of the American Chemical Society|September 21, 2012
Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitorsMichael P Storz, Christine K Maurer, Christina Zimmer, et al.International Journal of Cancer|February 10, 2015
The impact of stratifying by family history in colorectal cancer screening programsSimon Lucas Goede, Linda Rabeneck, Iris Lansdorp-Vogelaar, et al.Pageof 3