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Therapeutic Innovation & Regulatory Science|April 25, 2025
Incorporating Patient Input into the Target Product ProfileJean-Noel Talabardon, Janet E Church, Masanori Okuse, et al.
Particle and Fibre Toxicology|October 20, 2014
Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue modelAli Kermanizadeh, Mille Løhr, Martin Roursgaard, et al.
Molecular Cancer Research : MCR|March 4, 2008
Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expressionMichael Elser, Lubor Borsig, Paul O Hassa, et al.
Applied in Vitro Toxicology|September 21, 2020
Transcriptomic, Proteomic, and Functional Long-Term Characterization of Multicellular Three-Dimensional Human Liver MicrotissuesSimon Messner, Lisa Fredriksson, Volker M Lauschke, et al.
Nucleic Acids Research|June 8, 2010
PARP1 ADP-ribosylates lysine residues of the core histone tailsSimon Messner, Matthias Altmeyer, Hongtao Zhao, et al.
Archives of Toxicology|May 25, 2017
Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072Franziska Paech, Simon Messner, Jochen Spickermann, et al.
Molecular & Cellular Proteomics : MCP|March 1, 2015
Extending the limits of quantitative proteome profiling with data-independent acquisition and application to acetaminophen-treated three-dimensional liver microtissuesRoland Bruderer, Oliver M Bernhardt, Tejas Gandhi, et al.
Archives of Toxicology|June 15, 2017
Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injuryWilliam R Proctor, Alison J Foster, Jennifer Vogt, et al.
Clinical and Translational Science|June 8, 2018
Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology ModelingJeffrey L Woodhead, Franziska Paech, Martina Maurer, et al.
Nature Communications|November 8, 2016
Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmissionHimanish Ghosh, Luca Auguadri, Sereina Battaglia, et al.
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