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Cell Death & Disease|July 6, 2023
Pyruvate transamination and NAD biosynthesis enable proliferation of succinate dehydrogenase-deficient cells by supporting aerobic glycolysisLuisa Ricci, Federico Uchenna Stanley, Tanja Eberhart, et al.
The Biochemical Journal|May 10, 2011
Metabolic oxidative stress elicited by the copper(II) complex [Cu(isaepy)2] triggers apoptosis in SH-SY5Y cells through the induction of the AMP-activated protein kinase/p38MAPK/p53 signalling axis: evidence for a combined use with 3-bromopyruvate in neuroblastoma treatmentGiuseppe Filomeni, Simone Cardaci, Ana Maria Da Costa Ferreira, et al.
Autophagy|January 20, 2010
Carcinoma cells activate AMP-activated protein kinase-dependent autophagy as survival response to kaempferol-mediated energetic impairmentGiuseppe Filomeni, Enrico Desideri, Simone Cardaci, et al.
Carcinogenesis|May 2, 2009
The isatin-Schiff base copper(II) complex Cu(isaepy)2 acts as delocalized lipophilic cation, yields widespread mitochondrial oxidative damage and induces AMP-activated protein kinase-dependent apoptosisGiuseppe Filomeni, Sara Piccirillo, Ilaria Graziani, et al.
Mediators of Inflammation|October 23, 2015
S-Nitrosoglutathione Reductase Plays Opposite Roles in SH-SY5Y Models of Parkinson's Disease and Amyotrophic Lateral SclerosisSalvatore Rizza, Claudia Cirotti, Costanza Montagna, et al.
Cancer Research|July 10, 2012
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1Simone Cardaci, Salvatore Rizza, Giuseppe Filomeni, et al.
Nature Communications|December 14, 2020
D-mannose suppresses macrophage IL-1β productionSimone Torretta, Alessandra Scagliola, Luisa Ricci, et al.
Cancer Research|May 25, 2016
S-nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate DehydrogenaseSalvatore Rizza, Costanza Montagna, Simone Cardaci, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 28, 2018
S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagySalvatore Rizza, Simone Cardaci, Costanza Montagna, et al.
Cell Death & Disease|February 1, 2024
ACOD1 deficiency offers protection in a mouse model of diet-induced obesity by maintaining a healthy gut microbiotaTanja Eberhart, Federico Uchenna Stanley, Luisa Ricci, et al.
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