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Cell Death Discovery|June 11, 2024
Novel meriolin derivatives potently inhibit cell cycle progression and transcription in leukemia and lymphoma cells via inhibition of cyclin-dependent kinases (CDKs)Laura Schmitt, Julia Hoppe, Pablo Cea-Medina, et al.
The Journal of Biological Chemistry|October 1, 2025
A farnesoid X receptor T296I variant disrupts ligand-induced FXR activation and thus bile acid transport in progressive familial intrahepatic cholestasisAnnika Behrendt, Alex Bastianelli, Jan Stindt, et al.
The Plant Cell|August 1, 2019
Posttranslational Modification of the NADP-Malic Enzyme Involved in C4 Photosynthesis Modulates the Enzymatic Activity during the DayAnastasiia Bovdilova, Bruno M Alexandre, Astrid Höppner, et al.
The FEBS Journal|August 7, 2023
The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET)Hongli Zhang, Robert F Dierkes, Pablo Perez-Garcia, et al.
Scientific Reports|August 19, 2022
Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effectsMohanraj Gopalswamy, Tobias Kroeger, David Bickel, et al.
Journal of Medicinal Chemistry|July 21, 2021
Development of Cagrilintide, a Long-Acting Amylin AnalogueThomas Kruse, Jakob Lerche Hansen, Kirsten Dahl, et al.
Frontiers in Microbiology|October 14, 2024
Aplospojaveedins A-C, unusual sulfur-containing alkaloids produced by the endophytic fungus Aplosporella javeedii using OSMAC strategyYing Gao, Marian Frank, Nicole Teusch, et al.
Elife|June 14, 2023
Integrative dynamic structural biology unveils conformers essential for the oligomerization of a large GTPaseThomas-O Peulen, Carola S Hengstenberg, Ralf Biehl, et al.
Nature Communications|February 24, 2023
Enzyme adaptation to habitat thermal legacy shapes the thermal plasticity of marine microbiomesRamona Marasco, Marco Fusi, Cristina Coscolín, et al.
Genome Research|September 13, 2024
Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutationsAlicja Pacholewska, Matthias Lienhard, Mirko Brüggemann, et al.
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