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Expert Opinion on Therapeutic Patents
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July 13, 2019
Therapeutic modulation of retinoid X receptors - SAR and therapeutic potential of RXR ligands and recent patents
Simone Schierle, Daniel Merk
Methods in Molecular Biology (Clifton, N.J.)
|
July 25, 2018
Development of Nuclear Receptor Modulators
Simone Schierle, Daniel Merk
Chemmedchem
|
October 25, 2018
Selective Optimization of Pranlukast to Farnesoid X Receptor Modulators
Simone Schierle, Jurema Schmidt, Astrid Kaiser, et al.
Bioorganic & Medicinal Chemistry
|
July 21, 2018
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists
Jurema Schmidt, Simone Schierle, Leonie Gellrich, et al.
Journal of Medicinal Chemistry
|
October 11, 2021
Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1
Daniel Zaienne, Sabine Willems, Simone Schierle, et al.
Chemmedchem
|
May 30, 2019
Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα Modulator
Julius Pollinger, Simone Schierle, Sebastian Neumann, et al.
International Journal of Molecular Sciences
|
September 9, 2022
Activity Screening of Fatty Acid Mimetic Drugs Identified Nuclear Receptor Agonists
Moritz Helmstädter, Simone Schierle, Laura Isigkeit, et al.
Journal of Medicinal Chemistry
|
July 21, 2020
Design and Structural Optimization of Dual FXR/PPARδ Activators
Simone Schierle, Sebastian Neumann, Pascal Heitel, et al.
ACS Medicinal Chemistry Letters
|
February 19, 2021
A New FXR Ligand Chemotype with Agonist/Antagonist Switch
Moritz Helmstädter, Jan Vietor, Jana Sommer, et al.
Chemmedchem
|
April 15, 2021
Development and in vitro Profiling of Dual FXR/LTA4H Modulators
Simone Schierle, Steffen Brunst, Moritz Helmstädter, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 18) with videos related to
Sort By:
Page
of 2
Expert Opinion on Therapeutic Patents
|
July 13, 2019
Therapeutic modulation of retinoid X receptors - SAR and therapeutic potential of RXR ligands and recent patents
Simone Schierle, Daniel Merk
Methods in Molecular Biology (Clifton, N.J.)
|
July 25, 2018
Development of Nuclear Receptor Modulators
Simone Schierle, Daniel Merk
Chemmedchem
|
October 25, 2018
Selective Optimization of Pranlukast to Farnesoid X Receptor Modulators
Simone Schierle, Jurema Schmidt, Astrid Kaiser, et al.
Bioorganic & Medicinal Chemistry
|
July 21, 2018
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists
Jurema Schmidt, Simone Schierle, Leonie Gellrich, et al.
Journal of Medicinal Chemistry
|
October 11, 2021
Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1
Daniel Zaienne, Sabine Willems, Simone Schierle, et al.
Chemmedchem
|
May 30, 2019
Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα Modulator
Julius Pollinger, Simone Schierle, Sebastian Neumann, et al.
International Journal of Molecular Sciences
|
September 9, 2022
Activity Screening of Fatty Acid Mimetic Drugs Identified Nuclear Receptor Agonists
Moritz Helmstädter, Simone Schierle, Laura Isigkeit, et al.
Journal of Medicinal Chemistry
|
July 21, 2020
Design and Structural Optimization of Dual FXR/PPARδ Activators
Simone Schierle, Sebastian Neumann, Pascal Heitel, et al.
ACS Medicinal Chemistry Letters
|
February 19, 2021
A New FXR Ligand Chemotype with Agonist/Antagonist Switch
Moritz Helmstädter, Jan Vietor, Jana Sommer, et al.
Chemmedchem
|
April 15, 2021
Development and in vitro Profiling of Dual FXR/LTA4H Modulators
Simone Schierle, Steffen Brunst, Moritz Helmstädter, et al.
Page
of 2