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Journal of Medicinal Chemistry
|
November 19, 2025
Structural Biology Enabling Drug Discovery
David E Heppner, Simone V Bigi-Botterill, Andrew P Riley, et al.
ACS Medicinal Chemistry Letters
|
January 14, 2026
Fifteen Years, One Mission: Innovative, Inspirational, and Impactful Discoveries
Simone V Bigi-Botterill, Chiara Borsari, Amanda W Dombrowski, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 3, 2020
Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp<sup>3</sup> character and an exquisite selectivity profile
Simone V Bigi-Botterill, Anthony Ivetac, Erica L Bradshaw, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 26, 2015
Fragment-based drug discovery of potent and selective MKK3/6 inhibitors
Mark Adams, Toshitake Kobayashi, J David Lawson, et al.
Journal of Medicinal Chemistry
|
February 28, 2018
Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H-pyrazolo[3,4- c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibitors: Analysis of Structure-Kinetic Relationships
Masato Yoshikawa, Morihisa Saitoh, Taisuke Katoh, et al.
Journal of Medicinal Chemistry
|
March 30, 2021
Synthetic Approaches to the New Drugs Approved during 2019
Andrew C Flick, Carolyn A Leverett, Hong X Ding, et al.
ACS Medicinal Chemistry Letters
|
March 25, 2017
Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure
Marion Lanier, Jason Pickens, Simone V Bigi, et al.
Journal of Medicinal Chemistry
|
July 14, 2022
Synthetic Approaches to the New Drugs Approved During 2020
Andrew C Flick, Carolyn A Leverett, Hong X Ding, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
Correction to "Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure"
Marion Lanier, Jason Pickens, Simone V Bigi, et al.
Journal of Medicinal Chemistry
|
June 14, 2024
Design and Discovery of a Potent and Selective Inhibitor of Integrin αvβ1
Mark Sabat, Daniel W Carney, Gloria Hernandez-Torres, et al.
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of 1
Search research articles
Search
Showing results (1-10 of 10) with videos related to
Sort By:
Page
of 1
Journal of Medicinal Chemistry
|
November 19, 2025
Structural Biology Enabling Drug Discovery
David E Heppner, Simone V Bigi-Botterill, Andrew P Riley, et al.
ACS Medicinal Chemistry Letters
|
January 14, 2026
Fifteen Years, One Mission: Innovative, Inspirational, and Impactful Discoveries
Simone V Bigi-Botterill, Chiara Borsari, Amanda W Dombrowski, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 3, 2020
Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp<sup>3</sup> character and an exquisite selectivity profile
Simone V Bigi-Botterill, Anthony Ivetac, Erica L Bradshaw, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 26, 2015
Fragment-based drug discovery of potent and selective MKK3/6 inhibitors
Mark Adams, Toshitake Kobayashi, J David Lawson, et al.
Journal of Medicinal Chemistry
|
February 28, 2018
Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H-pyrazolo[3,4- c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibitors: Analysis of Structure-Kinetic Relationships
Masato Yoshikawa, Morihisa Saitoh, Taisuke Katoh, et al.
Journal of Medicinal Chemistry
|
March 30, 2021
Synthetic Approaches to the New Drugs Approved during 2019
Andrew C Flick, Carolyn A Leverett, Hong X Ding, et al.
ACS Medicinal Chemistry Letters
|
March 25, 2017
Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure
Marion Lanier, Jason Pickens, Simone V Bigi, et al.
Journal of Medicinal Chemistry
|
July 14, 2022
Synthetic Approaches to the New Drugs Approved During 2020
Andrew C Flick, Carolyn A Leverett, Hong X Ding, et al.
ACS Medicinal Chemistry Letters
|
December 21, 2017
Correction to "Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure"
Marion Lanier, Jason Pickens, Simone V Bigi, et al.
Journal of Medicinal Chemistry
|
June 14, 2024
Design and Discovery of a Potent and Selective Inhibitor of Integrin αvβ1
Mark Sabat, Daniel W Carney, Gloria Hernandez-Torres, et al.
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of 1