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Neurobiology of Aging|July 21, 2017
Alzheimer's disease markers in the aged sheep (Ovis aries)Suzanne J Reid, Natasha E Mckean, Kristen Henty, et al.Scientific Reports|February 12, 2016
Metabolic disruption identified in the Huntington's disease transgenic sheep modelRenee R Handley, Suzanne J Reid, Stefano Patassini, et al.Human Molecular Genetics|February 16, 2010
An ovine transgenic Huntington's disease modelJessie C Jacobsen, C Simon Bawden, Skye R Rudiger, et al.Journal of Huntington'S Disease|July 27, 2014
Further molecular characterisation of the OVT73 transgenic sheep model of Huntington's disease identifies cortical aggregates, Suzanne J Reid, Stefano Patassini, et al.Neurobiology of Aging|May 2, 2025
Presenilin 1 hemizygosity has no overt deleterious phenotypic outcomes in sheep: Potential implications for therapeutic targets in Alzheimer's diseaseNatasha E Mckean, Jun Liu, Skye R Rudiger, et al.Proceedings of the National Academy of Sciences of the United States of America|December 13, 2017
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD casesRenee R Handley, Suzanne J Reid, Rudiger Brauning, et al.Elife|July 6, 2021
Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated lociVictoria J Sugrue, Joseph Alan Zoller, Pritika Narayan, et al.Human Molecular Genetics|May 22, 2024
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease modelAndrew Jiang, Linya You, Renee R Handley, et al.Nature Communications|September 11, 2020
DNA methylation study of Huntington's disease and motor progression in patients and in animal modelsAke T Lu, Pritika Narayan, Matthew J Grant, et al.Journal of Huntington'S Disease|August 23, 2021
A Multi-Omic Huntington's Disease Transgenic Sheep-Model Database for Investigating Disease PathogenesisEmily R Mears, Renee R Handley, Matthew J Grant, et al.Pageof 3