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Journal of Medicinal Chemistry|August 14, 2020
A CNS-Targeting Prodrug Strategy for Nuclear Receptor ModulatorsSkylar J Ferrara, Thomas S Scanlan
Endocrinology|May 31, 2018
Hypothalamic-Pituitary-Thyroid Axis Perturbations in Male Mice by CNS-Penetrating ThyromimeticsSkylar J Ferrara, Dennis Bourdette, Thomas S Scanlan
Methods in Molecular Biology (Clifton, N.J.)|June 13, 2018
Quantification of Thyromimetic Sobetirome Concentration in Biological Tissue SamplesJordan Devereaux, Skylar J Ferrara, Thomas S Scanlan
Chemmedchem|October 13, 2016
Increasing Thyromimetic Potency through Halogen SubstitutionJordan Devereaux, Skylar J Ferrara, Tania Banerji, et al.
ACS Medicinal Chemistry Letters|January 19, 2019
Structure-Activity Relationships of Central Nervous System Penetration by Fatty Acid Amide Hydrolase (FAAH)-Targeted Thyromimetic ProdrugsJ Matthew Meinig, Skylar J Ferrara, Tapasree Banerji, et al.
Bioorganic & Medicinal Chemistry|October 7, 2016
Sobetirome prodrug esters with enhanced blood-brain barrier permeabilityAndrew T Placzek, Skylar J Ferrara, Meredith D Hartley, et al.
ACS Chemical Neuroscience|August 1, 2017
Targeting Fatty-Acid Amide Hydrolase with Prodrugs for CNS-Selective TherapyJ Matthew Meinig, Skylar J Ferrara, Tania Banerji, et al.
Biorxiv : the Preprint Server for Biology|February 3, 2021
TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptorSkylar J Ferrara, Priya Chaudhary, Margaret J DeBell, et al.
Cell Chemical Biology|August 10, 2021
TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptorSkylar J Ferrara, Priya Chaudhary, Margaret J DeBell, et al.
Bioorganic & Medicinal Chemistry|April 8, 2017
Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetrationSkylar J Ferrara, J Matthew Meinig, Andrew T Placzek, et al.
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