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Molecular and Cellular Endocrinology|November 19, 2023
Endosomal signaling via cAMP in parathyroid hormone (PTH) type 1 receptor biologyKarina A Peña, Sofya Savransky, Breanna Lewis
Cellular Signalling|March 24, 2024
Deciphering the role of glycosaminoglycans in GPCR signalingSofya Savransky, Alex D White, Jean-Pierre Vilardaga
Nature Communications|December 3, 2024
Fast-diffusing receptor collisions with slow-diffusing peptide ligand assemble the ternary parathyroid hormone-GPCR-arrestin complexJonathan Pacheco, Karina A Peña, Sofya Savransky, et al.
Communications Biology|June 2, 2023
Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken SyndromeIgnacio Portales-Castillo, Thomas Dean, Ross W Cheloha, et al.
The Journal of Biological Chemistry|August 6, 2022
Biased GPCR signaling by the native parathyroid hormone-related protein 1 to 141 relative to its N-terminal fragment 1 to 36Karina A Peña, Alex D White, Sofya Savransky, et al.
Medrxiv : the Preprint Server for Health Sciences|June 10, 2025
β-Amyloid as a new target to suppress tonic PTH hypersecretion in primary hyperparathyroidismChia-Ling Tu, Zhiqiang Cheng, Nicholas Szeto, et al.
Science Translational Medicine|March 18, 2026
Amyloid-β as a target to suppress tonic PTH hypersecretion in hyperparathyroidism due to vitamin D deficiencyChia-Ling Tu, Zhiqiang Cheng, Nicholas Szeto, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 26, 2025
Allosteric mechanism in the distinctive coupling of G<sub>q</sub> and G<sub>s</sub> to the parathyroid hormone type 1 receptorXuan Zhang, Ji Young Lee, Jonathan Pacheco, et al.
Nature Chemical Biology|February 3, 2026
Inhibitory probes for spatiotemporal analysis of Gα<sub>s</sub> protein signalingJingyi Zhao, Alex Luebbers, Sofya Savransky, et al.
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