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Cancers
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January 26, 2024
Small Molecule Immunomodulators as Next-Generation Therapeutics for Glioblastoma
Somaya A Abdel-Rahman, Moustafa Gabr
ACS Medicinal Chemistry Letters
|
July 14, 2026
High-Throughput CETSA Identifies Small Molecule Modulators of ILT3 (LILRB4) with Functional Activity in Human iPSC-Derived Microglia for Alzheimer's Disease
Somaya A Abdel-Rahman, Moustafa Gabr
Bioorganic & Medicinal Chemistry Letters
|
June 29, 2026
OracleScreen-LILRB4: machine learning-guided discovery of myeloid immune checkpoint binders validated in patient-derived cells
Somaya A Abdel-Rahman, Moustafa T Gabr
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|
July 6, 2026
From DNA-encoded library (DEL) screening to in vivo validation: LILRB4 (ILT3)-targeted small molecules reprograms myeloid immune suppression
Somaya A Abdel-Rahman, Moustafa T Gabr
Journal of Chemical Information and Modeling
|
July 13, 2026
HTS-Oracle v2: Prospective Ai-Guided Discovery and Experimental Validation of Small Molecule Modulators Across Multiple Targets
Somaya A Abdel-Rahman, Moustafa T Gabr
Science Advances
|
October 16, 2024
Small molecules from antibody pharmacophores (SMAbPs) as a hit identification workflow for immune checkpoints
Somaya A Abdel-Rahman, Moustafa T Gabr
SLAS Discovery : Advancing Life Sciences R & D
|
June 10, 2026
Development of a High-Throughput TR-FRET Assay for Identification of Small Molecule Inhibitors of the LILRB4 (ILT3)-SCG2 Immune Checkpoint Interaction
Somaya A Abdel-Rahman, Moustafa T Gabr
SLAS Discovery : Advancing Life Sciences R & D
|
May 20, 2025
Optimization and development of a high-throughput TR-FRET screening assay for SLIT2/ROBO1 interaction
Somaya A Abdel-Rahman, Moustafa T Gabr
European Journal of Medicinal Chemistry
|
May 14, 2025
First-in-class dual inhibitors of MASTL and Aurora A kinase: Discovery of selective cyclohexa[b]thiophenes with potent anticancer activity
Somaya A Abdel-Rahman, Hossam Nada, Moustafa T Gabr
ACS Medicinal Chemistry Letters
|
June 19, 2024
Structure-Based Rational Design of Constrained Peptides as TIM-3 Inhibitors
Somaya A Abdel-Rahman, Victor Ovchinnikov, Moustafa T Gabr
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Search research articles
Search
Showing results (1-10 of 33) with videos related to
Sort By:
Page
of 4
Cancers
|
January 26, 2024
Small Molecule Immunomodulators as Next-Generation Therapeutics for Glioblastoma
Somaya A Abdel-Rahman, Moustafa Gabr
ACS Medicinal Chemistry Letters
|
July 14, 2026
High-Throughput CETSA Identifies Small Molecule Modulators of ILT3 (LILRB4) with Functional Activity in Human iPSC-Derived Microglia for Alzheimer's Disease
Somaya A Abdel-Rahman, Moustafa Gabr
Bioorganic & Medicinal Chemistry Letters
|
June 29, 2026
OracleScreen-LILRB4: machine learning-guided discovery of myeloid immune checkpoint binders validated in patient-derived cells
Somaya A Abdel-Rahman, Moustafa T Gabr
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|
July 6, 2026
From DNA-encoded library (DEL) screening to in vivo validation: LILRB4 (ILT3)-targeted small molecules reprograms myeloid immune suppression
Somaya A Abdel-Rahman, Moustafa T Gabr
Journal of Chemical Information and Modeling
|
July 13, 2026
HTS-Oracle v2: Prospective Ai-Guided Discovery and Experimental Validation of Small Molecule Modulators Across Multiple Targets
Somaya A Abdel-Rahman, Moustafa T Gabr
Science Advances
|
October 16, 2024
Small molecules from antibody pharmacophores (SMAbPs) as a hit identification workflow for immune checkpoints
Somaya A Abdel-Rahman, Moustafa T Gabr
SLAS Discovery : Advancing Life Sciences R & D
|
June 10, 2026
Development of a High-Throughput TR-FRET Assay for Identification of Small Molecule Inhibitors of the LILRB4 (ILT3)-SCG2 Immune Checkpoint Interaction
Somaya A Abdel-Rahman, Moustafa T Gabr
SLAS Discovery : Advancing Life Sciences R & D
|
May 20, 2025
Optimization and development of a high-throughput TR-FRET screening assay for SLIT2/ROBO1 interaction
Somaya A Abdel-Rahman, Moustafa T Gabr
European Journal of Medicinal Chemistry
|
May 14, 2025
First-in-class dual inhibitors of MASTL and Aurora A kinase: Discovery of selective cyclohexa[b]thiophenes with potent anticancer activity
Somaya A Abdel-Rahman, Hossam Nada, Moustafa T Gabr
ACS Medicinal Chemistry Letters
|
June 19, 2024
Structure-Based Rational Design of Constrained Peptides as TIM-3 Inhibitors
Somaya A Abdel-Rahman, Victor Ovchinnikov, Moustafa T Gabr
Page
of 4