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Sommadossi

Showing results (91-100 of 175) with videos related to

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Molecular Pharmacology|February 1, 1991
Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cellsE M Cretton, M Y Xie, R J Bevan, et al.
Cancer Research|June 1, 1985
Evidence from rat hepatocytes of an unrecognized pathway of 5-fluorouracil metabolism with the formation of a glucuronide derivativeJ P Sommadossi, D S Cross, D A Gewirtz, et al.
Biochemical Pharmacology|January 10, 1997
Effect of stereoisomerism on the cellular pharmacology of beta-enantiomers of cytidine analogs in Hep-G2 cellsL T Martin, A Faraj, R F Schinazi, et al.
Nucleosides & Nucleotides|August 5, 1999
3'-(N-hydroxyimino)-2',3-dideoxynucleosides and their derivatives: synthesis, broad spectrum antiviral properties and synthetical application for the preparation of other nucleoside analoguesI Fedorov, E Kazmina, M Jasko, et al.
Antimicrobial Agents and Chemotherapy|September 1, 1993
In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidineE M Cretton, Z Zhou, L B Kidd, et al.
Biochemical Pharmacology|May 20, 1998
Role of human liver P450s and cytochrome b5 in the reductive metabolism of 3'-azido-3'-deoxythymidine (AZT) to 3'-amino-3'-deoxythymidineX R Pan-Zhou, E Cretton-Scott, X J Zhou, et al.
Cancer Chemotherapy and Pharmacology|January 1, 1995
Effects of 5-benzylacyclouridine, an inhibitor of uridine phosphorylase, on the pharmacokinetics of uridine in rhesus monkeys: implications for chemotherapyJ P Sommadossi, E M Cretton, L B Kidd, et al.
Bioorganic & Medicinal Chemistry|August 2, 2002
Synthesis and studies of 3'-C-trifluoromethyl nucleoside analogues bearing adenine or cytosine as the baseFrédéric Jeannot, Gilles Gosselin, David Standring, et al.
Plos Biology|August 27, 2024
The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolutionAurélie Chazot, Claire Zimberger, Mikael Feracci, et al.
Nucleosides, Nucleotides & Nucleic Acids|October 21, 2003
4'-C-methyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides revisitedJ F Griffon, D Dukhan, C Pierra, et al.
Pageof 18

Showing results (91-100 of 175) with videos related to

Sort By:
Pageof 18
Molecular Pharmacology|February 1, 1991
Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cellsE M Cretton, M Y Xie, R J Bevan, et al.
Cancer Research|June 1, 1985
Evidence from rat hepatocytes of an unrecognized pathway of 5-fluorouracil metabolism with the formation of a glucuronide derivativeJ P Sommadossi, D S Cross, D A Gewirtz, et al.
Biochemical Pharmacology|January 10, 1997
Effect of stereoisomerism on the cellular pharmacology of beta-enantiomers of cytidine analogs in Hep-G2 cellsL T Martin, A Faraj, R F Schinazi, et al.
Nucleosides & Nucleotides|August 5, 1999
3'-(N-hydroxyimino)-2',3-dideoxynucleosides and their derivatives: synthesis, broad spectrum antiviral properties and synthetical application for the preparation of other nucleoside analoguesI Fedorov, E Kazmina, M Jasko, et al.
Antimicrobial Agents and Chemotherapy|September 1, 1993
In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidineE M Cretton, Z Zhou, L B Kidd, et al.
Biochemical Pharmacology|May 20, 1998
Role of human liver P450s and cytochrome b5 in the reductive metabolism of 3'-azido-3'-deoxythymidine (AZT) to 3'-amino-3'-deoxythymidineX R Pan-Zhou, E Cretton-Scott, X J Zhou, et al.
Cancer Chemotherapy and Pharmacology|January 1, 1995
Effects of 5-benzylacyclouridine, an inhibitor of uridine phosphorylase, on the pharmacokinetics of uridine in rhesus monkeys: implications for chemotherapyJ P Sommadossi, E M Cretton, L B Kidd, et al.
Bioorganic & Medicinal Chemistry|August 2, 2002
Synthesis and studies of 3'-C-trifluoromethyl nucleoside analogues bearing adenine or cytosine as the baseFrédéric Jeannot, Gilles Gosselin, David Standring, et al.
Plos Biology|August 27, 2024
The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolutionAurélie Chazot, Claire Zimberger, Mikael Feracci, et al.
Nucleosides, Nucleotides & Nucleic Acids|October 21, 2003
4'-C-methyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides revisitedJ F Griffon, D Dukhan, C Pierra, et al.
Pageof 18