Showing results (381-390 of 391) with videos related to

Sort By:
Pageof 40
Cell Reports|January 17, 2026
Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 miceG Travis Tabor, Alexandra Litvinchuk, Yun Chen, et al.
The Journal of Clinical Investigation|December 4, 2012
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitorsMahadeo A Sukhai, Swayam Prabha, Rose Hurren, et al.
Biorxiv : the Preprint Server for Biology|October 1, 2025
A Common PD-Risk GBA1 Variant Disrupts LIMP2 Interaction, Impairs Glucocerebrosidase Function, and Drives Lysosomal and Mitochondrial DysfunctionOliver B Davis, Jennifer E Kung, Sonnet S Davis, et al.
Nature Communications|January 24, 2026
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonismAstrid F Feiten, Kilian Dahm, Kai Schlepckow, et al.
Cell|November 12, 2024
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomesJing L Guo, Dylan Braun, Gabriel A Fitzgerald, et al.
Science Translational Medicine|May 29, 2020
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in miceJulie C Ullman, Annie Arguello, Jennifer A Getz, et al.
The Journal of Clinical Endocrinology and Metabolism|May 28, 2009
The clinical variability of maternally inherited diabetes and deafness is associated with the degree of heteroplasmy in blood leukocytesM Laloi-Michelin, T Meas, C Ambonville, et al.
Molecular Neurodegeneration|June 11, 2022
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microgliaDan Xia, Steve Lianoglou, Thomas Sandmann, et al.
Science Translational Medicine|December 3, 2025
Loss of PILRA promotes microglial immunometabolism to reduce amyloid pathology in cell and mouse models of Alzheimer's diseaseTanya N Weerakkody, Hanna Sabelström, Shan V Andrews, et al.
Cell|August 27, 2021
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologicTodd Logan, Matthew J Simon, Anil Rana, et al.
Pageof 40