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Sophia Lin

Showing results (71-80 of 77) with videos related to

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Bioorganic & Medicinal Chemistry Letters|November 23, 2024
Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of Na<sub>V</sub>1.7Shaoyi Sun, Sultan Chowdhury, Ivan Hemeon, et al.
Science (New York, N.Y.)|December 19, 2015
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonistShivani Ahuja, Susmith Mukund, Lunbin Deng, et al.
British Journal of Pharmacology|June 26, 2024
The contribution of Na<sub>V</sub>1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na<sub>V</sub>1.6 gain-of-function (GOF) mouse seizure controlJames P Johnson, Thilo Focken, Parisa Karimi Tari, et al.
Journal of Medicinal Chemistry|December 1, 2018
Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na<sub>V</sub>) 1.7 with Potent Analgesic ActivityShaoyi Sun, Qi Jia, Alla Y Zenova, et al.
Journal of Medicinal Chemistry|May 9, 2018
Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa<sub>V</sub>1.7 Inhibitors for the Treatment of PainThilo Focken, Sultan Chowdhury, Alla Zenova, et al.
Elife|March 2, 2022
NBI-921352, a first-in-class, Na<sub>V</sub>1.6 selective, sodium channel inhibitor that prevents seizures in <i>Scn8a</i> gain-of-function mice, and wild-type mice and ratsJ P Johnson, Thilo Focken, Kuldip Khakh, et al.
Journal of Medicinal Chemistry|March 8, 2021
Discovery of Acyl-sulfonamide Na<sub>v</sub>1.7 Inhibitors GDC-0276 and GDC-0310Brian S Safina, Steven J McKerrall, Shaoyi Sun, et al.
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Showing results (71-80 of 77) with videos related to

Sort By:
Pageof 8
You have reached the last page of results.This site can display upto 77 results.
Bioorganic & Medicinal Chemistry Letters|November 23, 2024
Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of Na<sub>V</sub>1.7Shaoyi Sun, Sultan Chowdhury, Ivan Hemeon, et al.
Science (New York, N.Y.)|December 19, 2015
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonistShivani Ahuja, Susmith Mukund, Lunbin Deng, et al.
British Journal of Pharmacology|June 26, 2024
The contribution of Na<sub>V</sub>1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na<sub>V</sub>1.6 gain-of-function (GOF) mouse seizure controlJames P Johnson, Thilo Focken, Parisa Karimi Tari, et al.
Journal of Medicinal Chemistry|December 1, 2018
Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na<sub>V</sub>) 1.7 with Potent Analgesic ActivityShaoyi Sun, Qi Jia, Alla Y Zenova, et al.
Journal of Medicinal Chemistry|May 9, 2018
Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa<sub>V</sub>1.7 Inhibitors for the Treatment of PainThilo Focken, Sultan Chowdhury, Alla Zenova, et al.
Elife|March 2, 2022
NBI-921352, a first-in-class, Na<sub>V</sub>1.6 selective, sodium channel inhibitor that prevents seizures in <i>Scn8a</i> gain-of-function mice, and wild-type mice and ratsJ P Johnson, Thilo Focken, Kuldip Khakh, et al.
Journal of Medicinal Chemistry|March 8, 2021
Discovery of Acyl-sulfonamide Na<sub>v</sub>1.7 Inhibitors GDC-0276 and GDC-0310Brian S Safina, Steven J McKerrall, Shaoyi Sun, et al.
Pageof 8