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Proceedings of the National Academy of Sciences of the United States of America|October 18, 2022
Lysosomal positioning regulates Rab10 phosphorylation at LRRK2+ lysosomesJillian H Kluss, Alexandra Beilina, Chad D Williamson, et al.
Cell|February 21, 2023
Hallmarks of neurodegenerative diseasesDavid M Wilson, Mark R Cookson, Ludo Van Den Bosch, et al.
Biorxiv : the Preprint Server for Biology|February 14, 2024
Large structural variants in KOLF2.1J are unlikely to compromise neurological disease modellingMallory Ryan, Justin A McDonough, Michael E Ward, et al.
Nature Communications|August 9, 2023
Structure and regulation of full-length human leucine-rich repeat kinase 1Riley D Metcalfe, Juliana A Martinez Fiesco, Luis Bonet-Ponce, et al.
Stem Cell Research|October 9, 2021
Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matchedXylena Reed, Melanie M Cobb, Gaia Skinbinski, et al.
Molecular Neurodegeneration|March 20, 2021
Preclinical modeling of chronic inhibition of the Parkinson's disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivoJillian H Kluss, Melissa Conti Mazza, Yan Li, et al.
Plos One|January 22, 2010
The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylationAzad Kumar, Elisa Greggio, Alexandra Beilina, et al.
NPJ Parkinson'S Disease|May 1, 2018
Detection of endogenous S1292 LRRK2 autophosphorylation in mouse tissue as a readout for kinase activityJillian H Kluss, Melissa M Conti, Alice Kaganovich, et al.
Journal of Parkinson'S Disease|February 1, 2021
Combined Knockout of Lrrk2 and Rab29 Does Not Result in Behavioral Abnormalities in vivoMelissa Conti Mazza, Victoria Nguyen, Alexandra Beilina, et al.
Nature Communications|May 14, 2020
Integration of multiple biological contexts reveals principles of synthetic lethality that affect reproducibilityAngel A Ku, Hsien-Ming Hu, Xin Zhao, et al.
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