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Proceedings of the National Academy of Sciences of the United States of America|October 16, 2019
KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysisDana Rabara, Timothy H Tran, Srisathiyanarayanan Dharmaiah, et al.
Cell Reports|July 23, 2020
Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFRWupeng Yan, Evan Markegard, Srisathiyanarayanan Dharmaiah, et al.
Journal of the American Chemical Society|February 25, 2022
Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational DynamicsFa-An Chao, Srisathiyanarayanan Dharmaiah, Troy Taylor, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 3, 2016
Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδSrisathiyanarayanan Dharmaiah, Lakshman Bindu, Timothy H Tran, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 12, 2021
RAS interaction with Sin1 is dispensable for mTORC2 assembly and activityPau Castel, Srisathiyanarayanan Dharmaiah, Matthew J Sale, et al.
Communications Biology|June 2, 2023
Reduced dynamic complexity allows structure elucidation of an excited state of KRASFa-An Chao, Albert H Chan, Srisathiyanarayanan Dharmaiah, et al.
Science (New York, N.Y.)|September 11, 2025
Structural basis for LZTR1 recognition of RAS GTPases for degradationSrisathiyanarayanan Dharmaiah, Daniel A Bonsor, Stephanie P Mo, et al.
Scientific Reports|July 21, 2019
Structures of N-terminally processed KRAS provide insight into the role of N-acetylationSrisathiyanarayanan Dharmaiah, Timothy H Tran, Simon Messing, et al.
Nature Communications|February 20, 2021
KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activationTimothy H Tran, Albert H Chan, Lucy C Young, et al.
The Journal of Biological Chemistry|May 13, 2020
<i>RAS</i> internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signalingAndrew C Nelson, Thomas J Turbyville, Srisathiyanarayanan Dharmaiah, et al.
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