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Pharmaceutical Research|June 9, 2012
Preclinical pharmacokinetic and pharmacodynamic evaluation of novel anticancer agents, ON01910.Na (Rigosertib, Estybon™) and ON013105, for brain tumor chemotherapySilpa Nuthalapati, Qingyu Zhou, Ping Guo, et al.Bioorganic & Medicinal Chemistry|February 9, 2005
Design, synthesis, and biological evaluation of (E)- and (Z)-styryl-2-acetoxyphenyl sulfides and sulfones as cyclooxygenase-2 inhibitorsM V Ramana Reddy, Muralidhar Reddy Mallireddigari, Venkat R Pallela, et al.The Journal of Cell Biology|November 1, 2006
Activation of p38alpha/beta MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein CdoGiichi Takaesu, Jong-Sun Kang, Gyu-Un Bae, et al.Bioorganic & Medicinal Chemistry Letters|July 1, 2004
Synthesis of new coumarin 3-(N-aryl) sulfonamides and their anticancer activityNatala Srinivasa Reddy, Muralidhar Reddy Mallireddigari, Stephen Cosenza, et al.The Journal of Biological Chemistry|October 16, 2015
JNK-associated Leucine Zipper Protein Functions as a Docking Platform for Polo-like Kinase 1 and Regulation of the Associating Transcription Factor Forkhead Box Protein K1Poornima Ramkumar, Clement M Lee, Annie Moradian, et al.Molecular Cancer Therapeutics|February 27, 2014
Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor modelsXiaoping Zhang, Hua Lv, Qingyu Zhou, et al.Bioorganic & Medicinal Chemistry|February 15, 2008
Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitorsM V Ramana Reddy, Vinay K Billa, Venkat R Pallela, et al.Journal of Biochemistry|February 15, 2015
Identification and characterization of a cell division-regulating kinase AKB1 (associated kinase of Trypanosoma brucei 14-3-3) through proteomics study of the Tb14-3-3 binding proteinsMasahiro Inoue, Kenta Okamoto, Haruki Uemura, et al.Organic & Biomolecular Chemistry|February 7, 2013
Hydrothiolation of benzyl mercaptan to arylacetylene: application to the synthesis of (E) and (Z)-isomers of ON 01910·Na (Rigosertib®), a phase III clinical stage anti-cancer agentVenkat R Pallela, Muralidhar R Mallireddigari, Stephen C Cosenza, et al.Cell Reports|October 23, 2012
An in vivo functional screen uncovers miR-150-mediated regulation of hematopoietic injury responseBrian D Adams, Shangqin Guo, Haitao Bai, et al.Pageof 10