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Protein Engineering, Design & Selection : PEDS
|
March 7, 2015
Characterisation of de novo mutations in the C-terminal domain of proprotein convertase subtilisin/kexin type 9
Stefan Geschwindner, Gunilla M K Andersson, Hans-Georg Beisel, et al.
Biorxiv : the Preprint Server for Biology
|
February 23, 2026
Conformational dynamics at the pre-miR-377 Dicer site governs selective small-molecule recognition
Jacopo Manigrasso, Emeline Mestdach, Riccardo Quaia, et al.
The Biochemical Journal
|
November 8, 2014
Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7
Rachel H Church, Arjun Krishnakumar, Annika Urbanek, et al.
Journal of Medicinal Chemistry
|
January 26, 2023
Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction"
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, et al.
Journal of Medicinal Chemistry
|
February 2, 2022
Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, et al.
Plos One
|
February 24, 2018
Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion
Krister Bamberg, Ulrika Johansson, Karl Edman, et al.
Scientific Reports
|
June 15, 2026
Discovery of membrane channel modulators via DNA encoded library screening using native like membrane protein nanoparticles
Francesco V Reddavide, Trine L Toft-Bertelsen, Ieva Drulyte, et al.
Current Topics in Medicinal Chemistry
|
November 6, 2007
An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes
Jeffrey S Albert, Niklas Blomberg, Alexander L Breeze, et al.
Plos One
|
January 1, 2016
Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents
Ola Fjellström, Niklas Larsson, Shin-Ichiro Yasuda, et al.
Structure (London, England : 1993)
|
November 26, 2015
Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints
Karl Edman, Ali Hosseini, Magnus K Bjursell, et al.
Page
of 5
Search research articles
Search
Showing results (31-40 of 50) with videos related to
Sort By:
Page
of 5
Protein Engineering, Design & Selection : PEDS
|
March 7, 2015
Characterisation of de novo mutations in the C-terminal domain of proprotein convertase subtilisin/kexin type 9
Stefan Geschwindner, Gunilla M K Andersson, Hans-Georg Beisel, et al.
Biorxiv : the Preprint Server for Biology
|
February 23, 2026
Conformational dynamics at the pre-miR-377 Dicer site governs selective small-molecule recognition
Jacopo Manigrasso, Emeline Mestdach, Riccardo Quaia, et al.
The Biochemical Journal
|
November 8, 2014
Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7
Rachel H Church, Arjun Krishnakumar, Annika Urbanek, et al.
Journal of Medicinal Chemistry
|
January 26, 2023
Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction"
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, et al.
Journal of Medicinal Chemistry
|
February 2, 2022
Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, et al.
Plos One
|
February 24, 2018
Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion
Krister Bamberg, Ulrika Johansson, Karl Edman, et al.
Scientific Reports
|
June 15, 2026
Discovery of membrane channel modulators via DNA encoded library screening using native like membrane protein nanoparticles
Francesco V Reddavide, Trine L Toft-Bertelsen, Ieva Drulyte, et al.
Current Topics in Medicinal Chemistry
|
November 6, 2007
An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes
Jeffrey S Albert, Niklas Blomberg, Alexander L Breeze, et al.
Plos One
|
January 1, 2016
Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents
Ola Fjellström, Niklas Larsson, Shin-Ichiro Yasuda, et al.
Structure (London, England : 1993)
|
November 26, 2015
Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints
Karl Edman, Ali Hosseini, Magnus K Bjursell, et al.
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of 5