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Nature Chemical Biology|April 2, 2020
Selective covalent targeting of GPX4 using masked nitrile-oxide electrophilesJohn K Eaton, Laura Furst, Richard A Ruberto, et al.Journal of Medicinal Chemistry|June 16, 2012
Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2Mark Zak, Rohan Mendonca, Mercedesz Balazs, et al.Journal of Medicinal Chemistry|May 11, 2013
Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2Mark Zak, Christopher A Hurley, Stuart I Ward, et al.Cancer Cell|August 19, 2022
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant gliomaDiana D Shi, Milan R Savani, Michael M Levitt, et al.Pageof 3