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Nature|July 22, 2014
A vaccine targeting mutant IDH1 induces antitumour immunityTheresa Schumacher, Lukas Bunse, Stefan Pusch, et al.Blood|May 27, 2026
Mutant IDH1 blocks neutropoiesis by repressing myeloid progenitor programsMariam Hakobyan, Jens Langstein, María José Ramos Medina, et al.Science (New York, N.Y.)|January 8, 2026
IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutationJung Won Park, Jiehoon Kwak, Keon-Woo Kim, et al.Acta Neuropathologica|January 27, 2017
Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivoStefan Pusch, Sonja Krausert, Viktoria Fischer, et al.Journal of Neuro-Oncology|April 17, 2024
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokinesDaniela Kocher, Lei Cao, Romain Guiho, et al.Neuro-Oncology|August 17, 2022
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytomaFlorian Selt, Romain Sigaud, Gintvile Valinciute, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 12, 2018
The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic AstrocytomaJuliane L Buhl, Florian Selt, Thomas Hielscher, et al.Acta Neuropathologica|February 14, 2013
Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutationsDavid E Reuss, Rosario M Piro, David T W Jones, et al.Cancer Research|December 4, 2016
IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear PolaritySarah Chiang, Britta Weigelt, Huei-Chi Wen, et al.Nature Cancer|February 5, 2022
Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomasMirco Friedrich, Roman Sankowski, Lukas Bunse, et al.Pageof 9