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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|October 17, 2018
Serum- and Glucocorticoid-induced Kinase Sgk1 Directly Promotes the Differentiation of Colorectal Cancer Cells and Restrains MetastasisLennard Y W Lee, Connor Woolley, Thomas Starkey, et al.
Plos One|November 17, 2010
Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylationFrancesca Lessi, Andrew Beggs, Mariagrazia de Palo, et al.
Experimental and Molecular Pathology|November 4, 2008
Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutationsStefania Segditsas, Oliver M Sieber, Andrew Rowan, et al.
The Journal of Pathology|October 20, 2011
The C-terminus of Apc does not influence intestinal adenoma development or progressionAnnabelle Lewis, Hayley Davis, Maesha Deheragoda, et al.
International Journal of Cancer|August 28, 2007
Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinomaHeena Patel, Guadalupe Polanco-Echeverry, Stefania Segditsas, et al.
Gut|October 8, 2010
Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5Annabelle Lewis, Stefania Segditsas, Maesha Deheragoda, et al.
Nature Genetics|May 8, 2012
Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1Emma Jaeger, Simon Leedham, Annabelle Lewis, et al.
Human Molecular Genetics|September 11, 2008
Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and miceStefania Segditsas, Oliver Sieber, Maesha Deheragoda, et al.
Gut|January 31, 2012
A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tractsSimon J Leedham, Pedro Rodenas-Cuadrado, Kimberley Howarth, et al.
Gastroenterology|March 3, 2009
The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expressionPatrick Pollard, Maesha Deheragoda, Stefania Segditsas, et al.
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