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Frontiers in Oncology|March 31, 2023
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinomaCristina Di Giorgio, Rachele Bellini, Antonio Lupia, et al.
Biochemistry and Biophysics Reports|June 8, 2026
The Farnesoid X receptor-bile acid axis contributes to immune evasion in gastric cancer and its inhibition enhances efficacy of anti-PD-L1 therapyCristina Di Giorgio, Michele Biagioli, Silvia Marchianò, et al.
Translational Oncology|June 8, 2026
Pharmacological inhibition of LIF signaling reverses PD-L1-mediated immune suppression in gastric cancerCristina Di Giorgio, Silvia Marchianò, Michele Biagioli, et al.
Biochimica Et Biophysica Acta|January 12, 2010
The bile acid sensor FXR regulates insulin transcription and secretionBarbara Renga, Andrea Mencarelli, Piero Vavassori, et al.
Liver International : Official Journal of the International Association for the Study of the Liver|January 13, 2025
Liver GPBAR1 Associates With Immune Dysfunction in Primary Sclerosing Cholangitis and Its Activation Attenuates Cholestasis in Abcb4-/- MiceCristina Di Giorgio, Ginevra Urbani, Silvia Marchianò, et al.
Current Drug Targets. Immune, Endocrine and Metabolic Disorders|September 24, 2005
Role of FXR in regulating bile acid homeostasis and relevance for human diseasesGiovanni Rizzo, Barbara Renga, Andrea Mencarelli, et al.
Journal of Molecular Graphics & Modelling|November 18, 2005
Unveiling hidden features of orphan nuclear receptors: the case of the small heterodimer partner (SHP)Antonio Macchiarulo, Giovanni Rizzo, Gabriele Costantino, et al.
Current Medicinal Chemistry|November 28, 2009
Targetting farnesoid-X-receptor: from medicinal chemistry to disease treatmentStefano Fiorucci, Andrea Mencarelli, Elenora Distrutti, et al.
Biochemical Pharmacology|January 16, 2026
LIFR antagonism reverses epithelial pro-CAF programs in pancreatic ductal adenocarcinomaCristina Di Giorgio, Maria Rosaria Sette, Benedetta Sensini, et al.
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