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Steroids|November 27, 2015
Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activityValentina Sepe, Barbara Renga, Carmen Festa, et al.
Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids|July 21, 2019
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASHAdriana Carino, Michele Biagioli, Silvia Marchianò, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|April 24, 2003
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirinStefano Fiorucci, Eleonora Distrutti, Octavio Menezes de Lima, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 6, 2004
Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates antiadhesive properties of 2-(Acetyloxy)benzoic acid 3-(nitrooxymethyl)phenyl ester (NCX-4016) (NO-aspirin) on neutrophil-endothelial cell adherenceStefano Fiorucci, Eleonora Distrutti, Andrea Mencarelli, et al.
Current Topics in Medicinal Chemistry|February 20, 2007
Cyclo-oxygenase (COX) inhibiting nitric oxide donating (CINODs) drugs: a review of their current statusFiorucci Stefano, Eleonora Distrutti
Proceedings of the National Academy of Sciences of the United States of America|November 13, 2002
NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in miceStefano Fiorucci, Elisabetta Antonelli, Eleonora Distrutti, et al.
Marine Drugs|December 26, 2013
Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritisAndrea Mencarelli, Claudio D'Amore, Barbara Renga, et al.
The Journal of Pharmacology and Experimental Therapeutics|July 21, 2006
5-Amino-2-hydroxybenzoic acid 4-(5-thioxo-5H-[1,2]dithiol-3yl)-phenyl ester (ATB-429), a hydrogen sulfide-releasing derivative of mesalamine, exerts antinociceptive effects in a model of postinflammatory hypersensitivityEleonora Distrutti, Luca Sediari, Andrea Mencarelli, et al.
Journal of Immunology (Baltimore, Md. : 1950)|March 28, 2020
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver ToxicityMichele Biagioli, Adriana Carino, Chiara Fiorucci, et al.
European Journal of Pharmacology|May 11, 2011
Development of non-antibiotic macrolide that corrects inflammation-driven immune dysfunction in models of inflammatory bowel diseases and arthritisAndrea Mencarelli, Eleonora Distrutti, Barbara Renga, et al.
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