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Scientific Reports|February 12, 2016
Metabolic disruption identified in the Huntington's disease transgenic sheep modelRenee R Handley, Suzanne J Reid, Stefano Patassini, et al.Neurobiology of Disease|May 22, 2014
Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neuronsFranziska Richter, Fuying Gao, Vera Medvedeva, et al.Journal of Huntington'S Disease|July 27, 2014
Further molecular characterisation of the OVT73 transgenic sheep model of Huntington's disease identifies cortical aggregates, Suzanne J Reid, Stefano Patassini, et al.Proceedings of the National Academy of Sciences of the United States of America|December 13, 2017
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD casesRenee R Handley, Suzanne J Reid, Rudiger Brauning, et al.Human Molecular Genetics|May 22, 2024
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease modelAndrew Jiang, Linya You, Renee R Handley, et al.Journal of Huntington'S Disease|August 23, 2021
A Multi-Omic Huntington's Disease Transgenic Sheep-Model Database for Investigating Disease PathogenesisEmily R Mears, Renee R Handley, Matthew J Grant, et al.Scientific Reports|June 10, 2016
Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: metabolic basis for dementiaJingshu Xu, Paul Begley, Stephanie J Church, et al.Pageof 4