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Nature Chemical Biology|December 8, 2015
Molecular mechanism of respiratory syncytial virus fusion inhibitorsMichael B Battles, Johannes P Langedijk, Polina Furmanova-Hollenstein, et al.Chemical Research in Toxicology|June 16, 2023
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure-Activity Relationship ModelsDorota Herman, Maciej M Kańduła, Lorena G A Freitas, et al.Antiviral Research|December 29, 2023
A flexible, image-based, high-throughput platform encompassing in-depth cell profiling to identify broad-spectrum coronavirus antivirals with limited off-target effectsJordi Doijen, Inha Heo, Koen Temmerman, et al.Molecular Cancer Therapeutics|March 2, 2021
Discovery of JNJ-63576253, a Next-Generation Androgen Receptor Antagonist Active Against Wild-Type and Clinically Relevant Ligand Binding Domain Mutations in Metastatic Castration-Resistant Prostate CancerJonathan R Branch, Tammy L Bush, Vineet Pande, et al.Stem Cell Reports|July 31, 2018
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental PhenotypesAn Verheyen, Annick Diels, Joke Reumers, et al.Scientific Reports|August 9, 2020
Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell linesMichael J Cox, Steffen Jaensch, Jelle Van de Waeter, et al.Plos Pathogens|May 5, 2026
An orthoflavivirus inhibitor targeting multifunctional NS2A protein, a previously unidentified targetDoortje Borrenberghs, Kitti Wing Ki Chan, Sven Van Brandt, et al.Microorganisms|March 29, 2023
Identification of Z-Tyr-Ala-CHN<sub>2</sub>, a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2Jordi Doijen, Koen Temmerman, Christel Van den Eynde, et al.Nature Communications|August 2, 2017
Therapeutic efficacy of a respiratory syncytial virus fusion inhibitorDirk Roymans, Sarhad S Alnajjar, Michael B Battles, et al.Journal of Aerosol Medicine and Pulmonary Drug Delivery|May 8, 2026
Identification of an Inhaled Pulmonary Selective PDGFR Inhibitor with Sustained Target EngagementGlenn Marsboom, Tianbao Lu, Zhigang Hong, et al.Pageof 2