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Cell Reports|February 10, 2018
High-Sensitivity Fluorometry to Resolve Ion Channel Conformational DynamicsMatthias Wulf, Stephan Alexander Pless
Methods in Enzymology|June 14, 2021
Ion channel engineering using protein trans-splicingDebayan Sarkar, Hendrik Harms, Iacopo Galleano, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 10, 2021
Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Na<sub>v</sub>1.5Iacopo Galleano, Hendrik Harms, Koushik Choudhury, et al.
British Journal of Pharmacology|March 14, 2022
P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinityFederica Gasparri, Debayan Sarkar, Sarune Bielickaite, et al.
Biorxiv : the Preprint Server for Biology|February 8, 2024
Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore moduleKatharina Schott, Samuel George Usher, Oscar Serra, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 24, 2024
Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore regionKatharina Schott, Samuel George Usher, Oscar Serra, et al.
Biophysical Journal|October 22, 2019
Evolutionarily Conserved Interactions within the Pore Domain of Acid-Sensing Ion ChannelsMarina A Kasimova, Timothy Lynagh, Zeshan Pervez Sheikh, et al.
Biorxiv : the Preprint Server for Biology|December 23, 2024
Conformational plasticity of human acid-sensing ion channel 1aJames Cahill, Kimberly A Hartfield, Stephanie Andrea Heusser, et al.
Nature Communications|March 18, 2022
Structure-guided unlocking of Na<sub>X</sub> reveals a non-selective tetrodotoxin-sensitive cation channelCameron L Noland, Han Chow Chua, Marc Kschonsak, et al.
Cell Chemical Biology|December 19, 2023
Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channelsDebayan Sarkar, Iacopo Galleano, Stephanie Andrea Heusser, et al.
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