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Stephan Ort

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Biochemistry|July 10, 2010
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues Saugata Hazra, Stephan Ort, Manfred Konrad, et al.
Biochemical Pharmacology|December 10, 2013
A designed equine herpes thymidine kinase (EHV4 TK) variant improves ganciclovir-induced cell-killingTheresa McSorley, Stephan Ort, Christian Monnerjahn, et al.
Biochemistry|January 23, 2009
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinaseSaugata Hazra, Elisabetta Sabini, Stephan Ort, et al.
Biochemistry|March 1, 2011
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and releaseSaugata Hazra, Andrzej Szewczak, Stephan Ort, et al.
Nature Structural Biology|June 17, 2003
Structure of human dCK suggests strategies to improve anticancer and antiviral therapyElisabetta Sabini, Stephan Ort, Christian Monnerjahn, et al.
Journal of Molecular Biology|April 2, 2008
Structural basis for substrate promiscuity of dCKElisabetta Sabini, Saugata Hazra, Stephan Ort, et al.
FEBS Letters|February 9, 2008
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analoguesTheresa McSorley, Stephan Ort, Saugata Hazra, et al.
The Journal of Biological Chemistry|May 28, 2004
Substrate-induced conformational changes in human UMP/CMP kinaseDario Segura-Peña, Nikolina Sekulic, Stephan Ort, et al.
Biochemistry|January 13, 2006
Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganizationMichael H Godsey, Stephan Ort, Elisabetta Sabini, et al.
Journal of Molecular Biology|February 6, 2007
Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1Nikolina Sekulic, Kristen Dietrich, Ingo Paarmann, et al.
Pageof 2

Showing results (1-10 of 11) with videos related to

Sort By:
Pageof 2
Biochemistry|July 10, 2010
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues Saugata Hazra, Stephan Ort, Manfred Konrad, et al.
Biochemical Pharmacology|December 10, 2013
A designed equine herpes thymidine kinase (EHV4 TK) variant improves ganciclovir-induced cell-killingTheresa McSorley, Stephan Ort, Christian Monnerjahn, et al.
Biochemistry|January 23, 2009
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinaseSaugata Hazra, Elisabetta Sabini, Stephan Ort, et al.
Biochemistry|March 1, 2011
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and releaseSaugata Hazra, Andrzej Szewczak, Stephan Ort, et al.
Nature Structural Biology|June 17, 2003
Structure of human dCK suggests strategies to improve anticancer and antiviral therapyElisabetta Sabini, Stephan Ort, Christian Monnerjahn, et al.
Journal of Molecular Biology|April 2, 2008
Structural basis for substrate promiscuity of dCKElisabetta Sabini, Saugata Hazra, Stephan Ort, et al.
FEBS Letters|February 9, 2008
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analoguesTheresa McSorley, Stephan Ort, Saugata Hazra, et al.
The Journal of Biological Chemistry|May 28, 2004
Substrate-induced conformational changes in human UMP/CMP kinaseDario Segura-Peña, Nikolina Sekulic, Stephan Ort, et al.
Biochemistry|January 13, 2006
Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganizationMichael H Godsey, Stephan Ort, Elisabetta Sabini, et al.
Journal of Molecular Biology|February 6, 2007
Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1Nikolina Sekulic, Kristen Dietrich, Ingo Paarmann, et al.
Pageof 2