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Biochemistry
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August 18, 2012
Crystal structures of glutaminyl cyclases (QCs) from Drosophila melanogaster reveal active site conservation between insect and mammalian QCs
Birgit Koch, Petr Kolenko, Mirko Buchholz, et al.
Biochemistry
|
June 20, 2020
Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease
Oliver Kupski, Lisa-Marie Funk, Viktor Sautner, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
April 28, 2017
Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer's Disease-Studies on Relation to Effective Target Occupancy
Torsten Hoffmann, Antje Meyer, Ulrich Heiser, et al.
Biological Chemistry
|
September 28, 2010
Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
David Ruiz Carrillo, Christoph Parthier, Nadine Jänckel, et al.
Neurobiology of Aging
|
October 11, 2015
An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice
Jeffrey L Frost, Bin Liu, Jens-Ulrich Rahfeld, et al.
Journal of Alzheimer'S Disease : JAD
|
October 16, 2018
Dipeptidyl-Peptidase Activity of Meprin β Links N-truncation of Aβ with Glutaminyl Cyclase-Catalyzed pGlu-Aβ Formation
Dagmar Schlenzig, Holger Cynis, Maike Hartlage-Rübsamen, et al.
Biochemistry
|
June 16, 2011
Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center
David Ruiz-Carrillo, Birgit Koch, Christoph Parthier, et al.
ACS Chemical Neuroscience
|
April 30, 2025
Monomers, Dimers, and Oligomers of Pyroglutamate-Modified α-Synuclein Fragments Exhibit Distinct Biophysical Characteristics
Alexandra Bluhm, Wei Xiang, Frank Wien, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society
|
June 29, 2021
Focused ultrasound with anti-pGlu3 Aβ enhances efficacy in Alzheimer's disease-like mice via recruitment of peripheral immune cells
Tao Sun, Qiaoqiao Shi, Yongzhi Zhang, et al.
The Journal of Biological Chemistry
|
February 19, 2011
Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development
Stephan Schilling, Stephanie Kohlmann, Christoph Bäuscher, et al.
Page
of 10
Search research articles
Search
Showing results (71-80 of 96) with videos related to
Sort By:
Page
of 10
Biochemistry
|
August 18, 2012
Crystal structures of glutaminyl cyclases (QCs) from Drosophila melanogaster reveal active site conservation between insect and mammalian QCs
Birgit Koch, Petr Kolenko, Mirko Buchholz, et al.
Biochemistry
|
June 20, 2020
Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease
Oliver Kupski, Lisa-Marie Funk, Viktor Sautner, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
April 28, 2017
Glutaminyl Cyclase Inhibitor PQ912 Improves Cognition in Mouse Models of Alzheimer's Disease-Studies on Relation to Effective Target Occupancy
Torsten Hoffmann, Antje Meyer, Ulrich Heiser, et al.
Biological Chemistry
|
September 28, 2010
Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus
David Ruiz Carrillo, Christoph Parthier, Nadine Jänckel, et al.
Neurobiology of Aging
|
October 11, 2015
An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice
Jeffrey L Frost, Bin Liu, Jens-Ulrich Rahfeld, et al.
Journal of Alzheimer'S Disease : JAD
|
October 16, 2018
Dipeptidyl-Peptidase Activity of Meprin β Links N-truncation of Aβ with Glutaminyl Cyclase-Catalyzed pGlu-Aβ Formation
Dagmar Schlenzig, Holger Cynis, Maike Hartlage-Rübsamen, et al.
Biochemistry
|
June 16, 2011
Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center
David Ruiz-Carrillo, Birgit Koch, Christoph Parthier, et al.
ACS Chemical Neuroscience
|
April 30, 2025
Monomers, Dimers, and Oligomers of Pyroglutamate-Modified α-Synuclein Fragments Exhibit Distinct Biophysical Characteristics
Alexandra Bluhm, Wei Xiang, Frank Wien, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society
|
June 29, 2021
Focused ultrasound with anti-pGlu3 Aβ enhances efficacy in Alzheimer's disease-like mice via recruitment of peripheral immune cells
Tao Sun, Qiaoqiao Shi, Yongzhi Zhang, et al.
The Journal of Biological Chemistry
|
February 19, 2011
Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development
Stephan Schilling, Stephanie Kohlmann, Christoph Bäuscher, et al.
Page
of 10