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Stephen A Hitchcock

Showing results (1-10 of 21) with videos related to

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Current Opinion in Chemical Biology|April 26, 2008
Blood-brain barrier permeability considerations for CNS-targeted compound library designStephen A Hitchcock
Journal of Medicinal Chemistry|April 18, 2012
Structural modifications that alter the P-glycoprotein efflux properties of compoundsStephen A Hitchcock
Expert Opinion on Investigational Drugs|June 28, 2007
Targeting cannabinoid agonists for inflammatory and neuropathic painYuan Cheng, Stephen A Hitchcock
Journal of Medicinal Chemistry|December 22, 2006
Structure-brain exposure relationshipsStephen A Hitchcock, Lewis D Pennington
Bioorganic & Medicinal Chemistry Letters|October 10, 2012
Use of structure based design to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A (PDE10A) inhibitors against phosphodiesterase 3 (PDE3)Essa Hu, Roxanne K Kunz, Shannon Rumfelt, et al.
Biochemistry|November 26, 2009
Nonspecificity of binding of gamma-secretase modulators to the amyloid precursor proteinAndrew J Beel, Paul Barrett, Paul D Schnier, et al.
Neurobiology of Disease|February 10, 2015
Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesiaSean Austin O Lim, Rong Xia, Yunmin Ding, et al.
Bioorganic & Medicinal Chemistry Letters|May 11, 2012
Structure guided P1' modifications of HEA derived β-secretase inhibitors for the treatment of Alzheimer's diseaseHolger Monenschein, Daniel B Horne, Michael D Bartberger, et al.
Bioorganic & Medicinal Chemistry Letters|February 28, 2012
Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitorsEssa Hu, Roxanne K Kunz, Shannon Rumfelt, et al.
Bioorganic & Medicinal Chemistry Letters|December 9, 2008
Discovery of alpha-amidosulfones as potent and selective agonists of CB2: synthesis, SAR, and pharmacokinetic propertiesIsaac E Marx, Erin F DiMauro, Alan Cheng, et al.
Pageof 3

Showing results (1-10 of 21) with videos related to

Sort By:
Pageof 3
Current Opinion in Chemical Biology|April 26, 2008
Blood-brain barrier permeability considerations for CNS-targeted compound library designStephen A Hitchcock
Journal of Medicinal Chemistry|April 18, 2012
Structural modifications that alter the P-glycoprotein efflux properties of compoundsStephen A Hitchcock
Expert Opinion on Investigational Drugs|June 28, 2007
Targeting cannabinoid agonists for inflammatory and neuropathic painYuan Cheng, Stephen A Hitchcock
Journal of Medicinal Chemistry|December 22, 2006
Structure-brain exposure relationshipsStephen A Hitchcock, Lewis D Pennington
Bioorganic & Medicinal Chemistry Letters|October 10, 2012
Use of structure based design to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A (PDE10A) inhibitors against phosphodiesterase 3 (PDE3)Essa Hu, Roxanne K Kunz, Shannon Rumfelt, et al.
Biochemistry|November 26, 2009
Nonspecificity of binding of gamma-secretase modulators to the amyloid precursor proteinAndrew J Beel, Paul Barrett, Paul D Schnier, et al.
Neurobiology of Disease|February 10, 2015
Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesiaSean Austin O Lim, Rong Xia, Yunmin Ding, et al.
Bioorganic & Medicinal Chemistry Letters|May 11, 2012
Structure guided P1' modifications of HEA derived β-secretase inhibitors for the treatment of Alzheimer's diseaseHolger Monenschein, Daniel B Horne, Michael D Bartberger, et al.
Bioorganic & Medicinal Chemistry Letters|February 28, 2012
Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitorsEssa Hu, Roxanne K Kunz, Shannon Rumfelt, et al.
Bioorganic & Medicinal Chemistry Letters|December 9, 2008
Discovery of alpha-amidosulfones as potent and selective agonists of CB2: synthesis, SAR, and pharmacokinetic propertiesIsaac E Marx, Erin F DiMauro, Alan Cheng, et al.
Pageof 3