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Stephen B Shears

Showing results (71-80 of 108) with videos related to

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Proceedings of the National Academy of Sciences of the United States of America|March 2, 2021
Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell lineChunfang Gu, Juan Liu, Xiaojing Liu, et al.
Chemistry & Biology|April 29, 2014
Synthetic inositol phosphate analogs reveal that PPIP5K2 has a surface-mounted substrate capture site that is a target for drug discoveryHuanchen Wang, Himali Y Godage, Andrew M Riley, et al.
Biomolecules|June 28, 2023
Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid SignalingJia Yu, Barbara Leibiger, Shao-Nian Yang, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 29, 2017
KO of 5-InsP<sub>7</sub> kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotypeChunfang Gu, Hoai-Nghia Nguyen, Douglas Ganini, et al.
Biochemistry|October 1, 2015
Asp1 from Schizosaccharomyces pombe binds a [2Fe-2S](2+) cluster which inhibits inositol pyrophosphate 1-phosphatase activityHuanchen Wang, Vasudha S Nair, Ashley A Holland, et al.
Plos Genetics|March 29, 2018
Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouseRizwan Yousaf, Chunfang Gu, Zubair M Ahmed, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 6, 2020
Control of XPR1-dependent cellular phosphate efflux by InsP<sub>8</sub> is an exemplar for functionally-exclusive inositol pyrophosphate signalingXingyao Li, Chunfang Gu, Sarah Hostachy, et al.
Nature Communications|April 26, 2022
A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loopHuanchen Wang, Lalith Perera, Nikolaus Jork, et al.
Sub-Cellular Biochemistry|March 1, 2012
Defining signal transduction by inositol phosphatesStephen B Shears, Sindura B Ganapathi, Nikhil A Gokhale, et al.
Cell Reports|June 4, 2024
Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8Xingyao Li, Regan B Kirkpatrick, Xiaodong Wang, et al.
Pageof 11

Showing results (71-80 of 108) with videos related to

Sort By:
Pageof 11
Proceedings of the National Academy of Sciences of the United States of America|March 2, 2021
Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell lineChunfang Gu, Juan Liu, Xiaojing Liu, et al.
Chemistry & Biology|April 29, 2014
Synthetic inositol phosphate analogs reveal that PPIP5K2 has a surface-mounted substrate capture site that is a target for drug discoveryHuanchen Wang, Himali Y Godage, Andrew M Riley, et al.
Biomolecules|June 28, 2023
Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid SignalingJia Yu, Barbara Leibiger, Shao-Nian Yang, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 29, 2017
KO of 5-InsP<sub>7</sub> kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotypeChunfang Gu, Hoai-Nghia Nguyen, Douglas Ganini, et al.
Biochemistry|October 1, 2015
Asp1 from Schizosaccharomyces pombe binds a [2Fe-2S](2+) cluster which inhibits inositol pyrophosphate 1-phosphatase activityHuanchen Wang, Vasudha S Nair, Ashley A Holland, et al.
Plos Genetics|March 29, 2018
Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouseRizwan Yousaf, Chunfang Gu, Zubair M Ahmed, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 6, 2020
Control of XPR1-dependent cellular phosphate efflux by InsP<sub>8</sub> is an exemplar for functionally-exclusive inositol pyrophosphate signalingXingyao Li, Chunfang Gu, Sarah Hostachy, et al.
Nature Communications|April 26, 2022
A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loopHuanchen Wang, Lalith Perera, Nikolaus Jork, et al.
Sub-Cellular Biochemistry|March 1, 2012
Defining signal transduction by inositol phosphatesStephen B Shears, Sindura B Ganapathi, Nikhil A Gokhale, et al.
Cell Reports|June 4, 2024
Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8Xingyao Li, Regan B Kirkpatrick, Xiaodong Wang, et al.
Pageof 11