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Journal of Medicinal Chemistry|September 13, 2018
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase InhibitorsJustin R Harrison, Stephen Brand, Victoria Smith, et al.ACS Infectious Diseases|October 3, 2017
Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovaniLeah S Torrie, Stephen Brand, David A Robinson, et al.ACS Infectious Diseases|October 28, 2024
β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance ProfilingJopaul Mathew, Bo Zhou, Reagan S Haney, et al.ACS Infectious Diseases|November 2, 2018
Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovaniVictoriano Corpas-Lopez, Sonia Moniz, Michael Thomas, et al.Journal of Medicinal Chemistry|December 14, 2011
Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitorsStephen Brand, Laura A T Cleghorn, Stuart P McElroy, et al.Journal of Medicinal Chemistry|February 11, 2026
Identification of Compound 15 (MMV1581361) as a PfATP4 Inhibitor with Transmission-Blocking Activity and In Vivo Efficacy in a SCID Mouse Model of MalariaHenry A Onyame, Stephen Brand, Delphin Baud, et al.Journal of Medicinal Chemistry|April 27, 2021
Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral LeishmaniasisMichael Thomas, Stephen Brand, Manu De Rycker, et al.European Journal of Medicinal Chemistry|March 30, 2024
Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 proteinWilliam Nguyen, Coralie Boulet, Madeline G Dans, et al.Journal of Medicinal Chemistry|February 22, 2023
Optimization of 2,3-Dihydroquinazolinone-3-carboxamides as Antimalarials Targeting PfATP4Trent D Ashton, Madeline G Dans, Paola Favuzza, et al.Journal of Medicinal Chemistry|March 24, 2021
Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazinesDaniel L Priebbenow, Mitch Mathiew, Da-Hua Shi, et al.Pageof 5