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Journal of Medicinal Chemistry|November 21, 2014
Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasisStephen Brand, Neil R Norcross, Stephen Thompson, et al.European Journal of Medicinal Chemistry|July 18, 2024
Optimization of pyrazolopyridine 4-carboxamides with potent antimalarial activity for which resistance is associated with the P. falciparum transporter ABCI3Petar P S Calic, Trent D Ashton, Mahta Mansouri, et al.ACS Infectious Diseases|February 28, 2023
7-N-Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc1 ComplexWilliam Nguyen, Madeline G Dans, Iain Currie, et al.ACS Infectious Diseases|July 9, 2026
2-Amino-3,4-Dihydroquinazolines Exhibit Potent Antimalarial Activity by Targeting Plasmepsin XMadeline G Dans, Jon Kyle Awalt, Nghi Nguyen, et al.Chemmedchem|August 30, 2024
Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4Trent D Ashton, Petar P S Calic, Madeline G Dans, et al.Journal of Medicinal Chemistry|July 18, 2025
Optimization and Characterization of the Antimalarial Activity of N-Aryl Acetamides that are Susceptible to Mutations in ROM8 and CSC1William Nguyen, Coralie Boulet, Madeline G Dans, et al.Nature|April 3, 2010
N-myristoyltransferase inhibitors as new leads to treat sleeping sicknessJulie A Frearson, Stephen Brand, Stuart P McElroy, et al.Journal of Medicinal Chemistry|August 12, 2024
Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4Trent D Ashton, Petar P S Calic, Madeline G Dans, et al.European Journal of Medicinal Chemistry|October 10, 2024
Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome bJon Kyle Awalt, Wenyin Su, William Nguyen, et al.Journal of Medicinal Chemistry|August 29, 2017
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruziStephen Brand, Eun Jung Ko, Elisabet Viayna, et al.Pageof 5