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Drug Discovery Today
|
January 28, 2003
Function first: a powerful approach to post-genomic drug discovery
Stephen F Betz, Susan M Baxter, Jacquelyn S Fetrow
Biochemistry
|
January 5, 2005
The crystal structure of a quercetin 2,3-dioxygenase from Bacillus subtilis suggests modulation of enzyme activity by a change in the metal ion at the active site(s)
B Gopal, Lalima L Madan, Stephen F Betz, et al.
Journal of Medicinal Chemistry
|
January 20, 2006
Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor
Stephen F Betz, Greg J Reinhart, Francisco M Lio, et al.
Frontiers in Endocrinology
|
October 14, 2022
Somatostatin receptors in congenital hyperinsulinism: Biology to bedside
Mirjam E van Albada, Klaus Mohnike, Mark J Dunne, et al.
The Journal of Biological Chemistry
|
May 13, 2023
A selective nonpeptide somatostatin receptor 5 agonist effectively decreases insulin secretion in hyperinsulinism
Christine A Juliana, Jinghua Chai, Pablo Arroyo, et al.
Pituitary
|
January 9, 2022
Paltusotine, a novel oral once-daily nonpeptide SST2 receptor agonist, suppresses GH and IGF-1 in healthy volunteers
Ajay Madan, Stacy Markison, Stephen F Betz, et al.
Biochemical Pharmacology
|
June 6, 2006
Single amino acid residue determinants of non-peptide antagonist binding to the corticotropin-releasing factor1 (CRF1) receptor
Sam R J Hoare, Brock T Brown, Mark A Santos, et al.
Journal of Biomolecular Screening
|
November 6, 2003
A strategy for high-throughput assay development using leads derived from nuclear magnetic resonance-based screening
Philip J Hajduk, Stephen F Betz, Jamey Mack, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 18, 2020
Discovery of substituted 3H-pyrido[2,3-d]pyrimidin-4-ones as potent, biased, and orally bioavailable sst2 agonist
Jian Zhao, Zhiyong Chen, Ana Karin Kusnetzow, et al.
Journal of Medicinal Chemistry
|
October 13, 2006
Determination of the binding mode of thienopyrimidinedione antagonists to the human gonadotropin releasing hormone receptor using structure-activity relationships, site-directed mutagenesis, and homology modeling
Stephen F Betz, Francisco M Lio, Yinghong Gao, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 20) with videos related to
Sort By:
Page
of 2
Drug Discovery Today
|
January 28, 2003
Function first: a powerful approach to post-genomic drug discovery
Stephen F Betz, Susan M Baxter, Jacquelyn S Fetrow
Biochemistry
|
January 5, 2005
The crystal structure of a quercetin 2,3-dioxygenase from Bacillus subtilis suggests modulation of enzyme activity by a change in the metal ion at the active site(s)
B Gopal, Lalima L Madan, Stephen F Betz, et al.
Journal of Medicinal Chemistry
|
January 20, 2006
Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor
Stephen F Betz, Greg J Reinhart, Francisco M Lio, et al.
Frontiers in Endocrinology
|
October 14, 2022
Somatostatin receptors in congenital hyperinsulinism: Biology to bedside
Mirjam E van Albada, Klaus Mohnike, Mark J Dunne, et al.
The Journal of Biological Chemistry
|
May 13, 2023
A selective nonpeptide somatostatin receptor 5 agonist effectively decreases insulin secretion in hyperinsulinism
Christine A Juliana, Jinghua Chai, Pablo Arroyo, et al.
Pituitary
|
January 9, 2022
Paltusotine, a novel oral once-daily nonpeptide SST2 receptor agonist, suppresses GH and IGF-1 in healthy volunteers
Ajay Madan, Stacy Markison, Stephen F Betz, et al.
Biochemical Pharmacology
|
June 6, 2006
Single amino acid residue determinants of non-peptide antagonist binding to the corticotropin-releasing factor1 (CRF1) receptor
Sam R J Hoare, Brock T Brown, Mark A Santos, et al.
Journal of Biomolecular Screening
|
November 6, 2003
A strategy for high-throughput assay development using leads derived from nuclear magnetic resonance-based screening
Philip J Hajduk, Stephen F Betz, Jamey Mack, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 18, 2020
Discovery of substituted 3H-pyrido[2,3-d]pyrimidin-4-ones as potent, biased, and orally bioavailable sst2 agonist
Jian Zhao, Zhiyong Chen, Ana Karin Kusnetzow, et al.
Journal of Medicinal Chemistry
|
October 13, 2006
Determination of the binding mode of thienopyrimidinedione antagonists to the human gonadotropin releasing hormone receptor using structure-activity relationships, site-directed mutagenesis, and homology modeling
Stephen F Betz, Francisco M Lio, Yinghong Gao, et al.
Page
of 2