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Clinical Pharmacology and Therapeutics|December 12, 2017
Model-Based Assessments of CYP-Mediated Drug-Drug Interaction Risk of Alectinib: Physiologically Based Pharmacokinetic Modeling Supported Clinical DevelopmentYumi Cleary, Michael Gertz, Peter N Morcos, et al.
Clinical Pharmacology and Therapeutics|April 5, 2023
Dose Adjustment in Patients with Liver Cirrhosis - Comparison of Two Different Modeling ApproachesAgustos C Ozbey, Fabio Bachmann, Urs Duthaler, et al.
Molecular Pharmaceutics|February 27, 2013
In vitro to in vivo extrapolation and physiologically based modeling of cytochrome P450 mediated metabolism in beagle dog gut wall and liverAki T Heikkinen, Stephen Fowler, Lynn Gray, et al.
ERJ Open Research|September 3, 2025
Enhancing severe asthma care: real-world outcomes of a digital adherence and self-management platformLaura Wiffen, Lynn Elsey, Thomas P Brown, et al.
The AAPS Journal|November 6, 2020
Correction to: In Vitro to In Vivo Extrapolation of Metabolic Clearance for UGT Substrates Using Short-Term Suspension and Long-Term Co-cultured Human HepatocytesLuca Docci, Florian Klammers, Aynur Ekiciler, et al.
The AAPS Journal|October 14, 2020
In Vitro to In Vivo Extrapolation of Metabolic Clearance for UGT Substrates Using Short-Term Suspension and Long-Term Co-cultured Human HepatocytesLuca Docci, Florian Klammers, Aynur Ekiciler, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|September 26, 2015
Shedding light on minipig drug metabolism - elevated amide hydrolysis in vitroRussell Jones, Michaela Marschmann, Michael Keller, et al.
Antimicrobial Agents and Chemotherapy|September 2, 2009
Nonclinical pharmacokinetics of oseltamivir and oseltamivir carboxylate in the central nervous systemGerhard Hoffmann, Christoph Funk, Stephen Fowler, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 23, 2024
Physiologically Based Pharmacokinetic Modeling to Predict the Impact of Liver Cirrhosis on Glucuronidation via UGT1A4 and UGT2B7/2B4-A Case Study with MidazolamAgustos C Ozbey, Janneke Keemink, Bjoern Wagner, et al.
Scientific Reports|March 13, 2019
The In Vitro Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1Simone Schadt, Christophe Husser, Roland F Staack, et al.
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