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Stephen Hanessian

Showing results (141-150 of 154) with videos related to

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ACS Medicinal Chemistry Letters|May 22, 2020
Synthetic Sphingolipids with 1,2-Pyridazine Appendages Improve Antiproliferative Activity in Human Cancer Cell LinesSylvestre P J T Bachollet, Vito Vece, Alison N McCracken, et al.
Journal of Medicinal Chemistry|April 27, 2007
Structure-based design, synthesis, and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2" ether analogues of paromomycinStephen Hanessian, Janek Szychowski, Susanta Sekhar Adhikari, et al.
ACS Chemical Biology|December 15, 2015
Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in VivoBin Chen, Saurabh G Roy, Ryan J McMonigle, et al.
Bioorganic & Medicinal Chemistry|August 1, 2016
Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell deathMichael S Perryman, Jérémie Tessier, Timothy Wiher, et al.
Bioorganic & Medicinal Chemistry Letters|August 7, 2019
Design, synthesis and anticancer activity of constrained sphingolipid-phenoxazine/phenothiazine hybrid constructs targeting protein phosphatase 2AJean-Baptiste Garsi, Vito Vece, Lorenzo Sernissi, et al.
Journal of the American Chemical Society|January 18, 2022
Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Nucleic Acids Research|February 2, 2023
Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeuticsBrendan T Finicle, Kazumi H Eckenstein, Alexey S Revenko, et al.
Journal of Medicinal Chemistry|August 5, 2005
Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimeticsStephen Hanessian, Hongying Yun, Yihua Hou, et al.
EMBO Molecular Medicine|July 7, 2021
Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesityVaishali Jayashankar, Elizabeth Selwan, Sarah E Hancock, et al.
ACS Chemical Biology|July 15, 2014
Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogsJuan Pablo Maianti, Hiroki Kanazawa, Paola Dozzo, et al.
Pageof 16

Showing results (141-150 of 154) with videos related to

Sort By:
Pageof 16
ACS Medicinal Chemistry Letters|May 22, 2020
Synthetic Sphingolipids with 1,2-Pyridazine Appendages Improve Antiproliferative Activity in Human Cancer Cell LinesSylvestre P J T Bachollet, Vito Vece, Alison N McCracken, et al.
Journal of Medicinal Chemistry|April 27, 2007
Structure-based design, synthesis, and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2" ether analogues of paromomycinStephen Hanessian, Janek Szychowski, Susanta Sekhar Adhikari, et al.
ACS Chemical Biology|December 15, 2015
Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in VivoBin Chen, Saurabh G Roy, Ryan J McMonigle, et al.
Bioorganic & Medicinal Chemistry|August 1, 2016
Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell deathMichael S Perryman, Jérémie Tessier, Timothy Wiher, et al.
Bioorganic & Medicinal Chemistry Letters|August 7, 2019
Design, synthesis and anticancer activity of constrained sphingolipid-phenoxazine/phenothiazine hybrid constructs targeting protein phosphatase 2AJean-Baptiste Garsi, Vito Vece, Lorenzo Sernissi, et al.
Journal of the American Chemical Society|January 18, 2022
Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Nucleic Acids Research|February 2, 2023
Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeuticsBrendan T Finicle, Kazumi H Eckenstein, Alexey S Revenko, et al.
Journal of Medicinal Chemistry|August 5, 2005
Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimeticsStephen Hanessian, Hongying Yun, Yihua Hou, et al.
EMBO Molecular Medicine|July 7, 2021
Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesityVaishali Jayashankar, Elizabeth Selwan, Sarah E Hancock, et al.
ACS Chemical Biology|July 15, 2014
Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogsJuan Pablo Maianti, Hiroki Kanazawa, Paola Dozzo, et al.
Pageof 16