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Journal of Medicinal Chemistry|January 22, 2005
Extension of the Nenitzescu reaction to simple ketones provides an efficient route to 1'-alkyl-5'-hydroxynaltrindole analogues, potent and selective delta-opioid receptor antagonistsShefali Shefali, Sanjay K Srivastava, Stephen M Husbands, et al.Journal of Medicinal Chemistry|October 1, 2004
Identification of a new scaffold for opioid receptor antagonism based on the 2-amino-1,1-dimethyl-7-hydroxytetralin pharmacophorePeter Grundt, Ian A Williams, John W Lewis, et al.Journal of Psychopharmacology (Oxford, England)|June 6, 2015
Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in miceAbdulrahman Almatroudi, Stephen M Husbands, Christopher P Bailey, et al.Journal of Medicinal Chemistry|June 27, 2003
Opioid binding and in vitro profiles of a series of 4-hdroxy-3-methoxyindolomorphinans. Transformation of a delta-selective ligand into a high affinity kappa-selective ligand by introduction of a 5,14-substituted bridgePeter Grundt, Fernando Martinez-Bermejo, John W Lewis, et al.Chemistry & Biodiversity|December 29, 2006
Formic acid catalysed rearrangement of 5beta-methyldihydrothevinols (= 3,6-dimethoxy-5,17-dimethyl-4,5-epoxy-6,14-ethanomorphinan-7-methanols): synthesis of new doubly bridged morphinan derivativesDavid Rennison, Peter Grundt, Claire Goodyer, et al.Journal of Labelled Compounds & Radiopharmaceuticals|December 12, 2013
Palladium-mediated oxidative carbonylation reactions for the synthesis of (11) C-radiolabelled ureasSteven Kealey, Stephen M Husbands, Idriss Bennacef, et al.The Journal of Pharmacology and Experimental Therapeutics|May 9, 2013
Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/μ-opioid receptor ligands in mouse models of neuropathic and inflammatory painDevki D Sukhtankar, Nurulain T Zaveri, Stephen M Husbands, et al.Basic & Clinical Pharmacology & Toxicology|April 7, 2024
Effects of sex and hydration status on kappa opioid receptor-mediated diuresis in ratsHasnain M Lalji, Christopher P Bailey, Stephen M Husbands, et al.ACS Medicinal Chemistry Letters|February 28, 2012
Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) ProteinsEmma M Turner, Levi L Blazer, Richard R Neubig, et al.European Journal of Pharmacology|May 13, 2014
Novel mixed NOP/MOP agonist BU08070 alleviates pain and inhibits gastrointestinal motility in mouse models mimicking diarrhea-predominant irritable bowel syndrome symptomsMarta Sobczak, Gerta Cami-Kobeci, Maciej Sałaga, et al.Pageof 11