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The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|January 11, 2013
Oral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after spinal cord injuryChhavy Tep, Tae Hee Lim, Pyung On Ko, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|May 19, 2006
Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced deathStephen M Massa, Youmei Xie, Tao Yang, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|August 28, 2009
The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivoJuliet K Knowles, Jayakumar Rajadas, Thuy-Vi V Nguyen, et al.Human Molecular Genetics|February 8, 2017
A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD miceDanielle A Simmons, Nadia P Belichenko, Ellen C Ford, et al.Nature Medicine|May 17, 2024
p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trialHayley R C Shanks, Kewei Chen, Eric M Reiman, et al.Journal of Alzheimer'S Disease : JAD|June 6, 2014
Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic miceThuy-Vi V Nguyen, Lin Shen, Lilith Vander Griend, et al.Plos One|November 4, 2008
Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairmentTao Yang, Juliet K Knowles, Qun Lu, et al.Stroke|April 27, 2012
Delayed administration of a small molecule tropomyosin-related kinase B ligand promotes recovery after hypoxic-ischemic strokeJullet Han, Julia Pollak, Tao Yang, et al.The Journal of Biological Chemistry|April 15, 2006
Protein-tyrosine phosphatase (PTP) wedge domain peptides: a novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase functionYoumei Xie, Stephen M Massa, Sonya E Ensslen-Craig, et al.Neurobiology of Aging|April 3, 2013
Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse modelJuliet K Knowles, Danielle A Simmons, Thuy-Vi V Nguyen, et al.Pageof 5