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Journal of Medicinal Chemistry
|
February 2, 2024
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390
Kurt G Pike, Thomas A Hunt, Bernard Barlaam, et al.
Nature Communications
|
May 24, 2024
H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
Diego Dibitetto, Martin Liptay, Francesca Vivalda, et al.
Journal of Medicinal Chemistry
|
April 24, 2018
The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2 H-pyran-4-yl)-1,3-dihydro-2 H-imidazo[4,5- c]quinolin-2-one)
Kurt G Pike, Bernard Barlaam, Elaine Cadogan, et al.
Science Advances
|
June 26, 2018
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models
Stephen T Durant, Li Zheng, Yingchun Wang, et al.
Molecular Cancer Therapeutics
|
May 18, 2018
Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice
Jeremy Karlin, Jasmine Allen, Syed F Ahmad, et al.
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Showing results (21-30 of 25) with videos related to
Sort By:
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This site can display upto 25 results.
Journal of Medicinal Chemistry
|
February 2, 2024
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390
Kurt G Pike, Thomas A Hunt, Bernard Barlaam, et al.
Nature Communications
|
May 24, 2024
H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
Diego Dibitetto, Martin Liptay, Francesca Vivalda, et al.
Journal of Medicinal Chemistry
|
April 24, 2018
The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2 H-pyran-4-yl)-1,3-dihydro-2 H-imidazo[4,5- c]quinolin-2-one)
Kurt G Pike, Bernard Barlaam, Elaine Cadogan, et al.
Science Advances
|
June 26, 2018
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models
Stephen T Durant, Li Zheng, Yingchun Wang, et al.
Molecular Cancer Therapeutics
|
May 18, 2018
Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice
Jeremy Karlin, Jasmine Allen, Syed F Ahmad, et al.
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of 3