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Journal of Medicinal Chemistry
|
July 15, 2020
Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent <i>In Vitro</i> Antileishmanial Activity: Initial SAR and Assessment of <i>In Vivo</i> Activity
Michael G Thomas, Manu De Rycker, Richard J Wall, et al.
Journal of Medicinal Chemistry
|
June 21, 2023
Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues
Laura A T Cleghorn, Richard J Wall, Sébastien Albrecht, et al.
Journal of Medicinal Chemistry
|
April 27, 2021
Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis
Michael Thomas, Stephen Brand, Manu De Rycker, et al.
Journal of Medicinal Chemistry
|
November 21, 2014
Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis
Stephen Brand, Neil R Norcross, Stephen Thompson, et al.
ACS Infectious Diseases
|
February 27, 2025
Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of <i>Mycobacterium tuberculosis</i>
Simon R Green, Justin R Harrison, Stephen Thompson, et al.
RSC Medicinal Chemistry
|
January 22, 2021
Identification of 6-amino-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidines with <i>in vivo</i> efficacy against visceral leishmaniasis
Michael G Thomas, Manu De Rycker, Myriam Ajakane, et al.
Medicinal Research Reviews
|
December 14, 2004
Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets
Justine Y Q Lai, Steven Langston, Ruth Adams, et al.
Journal of Medicinal Chemistry
|
August 29, 2017
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi
Stephen Brand, Eun Jung Ko, Elisabet Viayna, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
April 10, 2019
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
Susan Wyllie, Stephen Brand, Michael Thomas, et al.
Journal of Medicinal Chemistry
|
December 21, 2018
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Michael G Thomas, Manu De Rycker, Myriam Ajakane, et al.
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of 14
Search research articles
Search
Showing results (131-140 of 140) with videos related to
Sort By:
Page
of 14
You have reached the last page of results.
This site can display upto 140 results.
Journal of Medicinal Chemistry
|
July 15, 2020
Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent <i>In Vitro</i> Antileishmanial Activity: Initial SAR and Assessment of <i>In Vivo</i> Activity
Michael G Thomas, Manu De Rycker, Richard J Wall, et al.
Journal of Medicinal Chemistry
|
June 21, 2023
Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues
Laura A T Cleghorn, Richard J Wall, Sébastien Albrecht, et al.
Journal of Medicinal Chemistry
|
April 27, 2021
Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis
Michael Thomas, Stephen Brand, Manu De Rycker, et al.
Journal of Medicinal Chemistry
|
November 21, 2014
Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis
Stephen Brand, Neil R Norcross, Stephen Thompson, et al.
ACS Infectious Diseases
|
February 27, 2025
Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of <i>Mycobacterium tuberculosis</i>
Simon R Green, Justin R Harrison, Stephen Thompson, et al.
RSC Medicinal Chemistry
|
January 22, 2021
Identification of 6-amino-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidines with <i>in vivo</i> efficacy against visceral leishmaniasis
Michael G Thomas, Manu De Rycker, Myriam Ajakane, et al.
Medicinal Research Reviews
|
December 14, 2004
Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets
Justine Y Q Lai, Steven Langston, Ruth Adams, et al.
Journal of Medicinal Chemistry
|
August 29, 2017
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi
Stephen Brand, Eun Jung Ko, Elisabet Viayna, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
April 10, 2019
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
Susan Wyllie, Stephen Brand, Michael Thomas, et al.
Journal of Medicinal Chemistry
|
December 21, 2018
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Michael G Thomas, Manu De Rycker, Myriam Ajakane, et al.
Page
of 14