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Stephen V Frye

Showing results (21-30 of 126) with videos related to

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Molecular Cell|July 19, 2025
Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markersChien-Chu Lin, Yani Zhao, Caroline A Foley, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2016
Design, synthesis, and protein methyltransferase activity of a unique set of constrained amine containing compoundsHao Zhou, Xin Che, Guochen Bao, et al.
SLAS Discovery : Advancing Life Sciences R & D|April 25, 2019
A General TR-FRET Assay Platform for High-Throughput Screening and Characterizing Inhibitors of Methyl-Lysine Reader ProteinsJustin M Rectenwald, P Brian Hardy, Jacqueline L Norris-Drouin, et al.
Nature Reviews. Drug Discovery|September 22, 2015
Tackling reproducibility in academic preclinical drug discoveryStephen V Frye, Michelle R Arkin, Cheryl H Arrowsmith, et al.
Journal of Biomolecular Screening|December 17, 2009
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteinsTim J Wigle, J Martin Herold, Guillermo A Senisterra, et al.
Plos One|June 22, 2017
Retraction: A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase InhibitorsBrandi M Baughman, Huanchen Wang, Yi An, et al.
ACS Chemical Biology|June 30, 2016
Chromodomain Ligand Optimization via Target-Class Directed Combinatorial RepurposingKimberly D Barnash, Kelsey N Lamb, Jacob I Stuckey, et al.
Journal of Medicinal Chemistry|May 17, 2021
Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1)Isabelle A Engelberg, Jiuyang Liu, Jacqueline L Norris-Drouin, et al.
Journal of Medicinal Chemistry|August 1, 2012
Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonistsXin Chen, Maria F Sassano, Lianyou Zheng, et al.
Plos One|October 14, 2016
A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase InhibitorsBrandi M Baughman, Huanchen Wang, Yi An, et al.
Pageof 13

Showing results (21-30 of 126) with videos related to

Sort By:
Pageof 13
Molecular Cell|July 19, 2025
Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markersChien-Chu Lin, Yani Zhao, Caroline A Foley, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2016
Design, synthesis, and protein methyltransferase activity of a unique set of constrained amine containing compoundsHao Zhou, Xin Che, Guochen Bao, et al.
SLAS Discovery : Advancing Life Sciences R & D|April 25, 2019
A General TR-FRET Assay Platform for High-Throughput Screening and Characterizing Inhibitors of Methyl-Lysine Reader ProteinsJustin M Rectenwald, P Brian Hardy, Jacqueline L Norris-Drouin, et al.
Nature Reviews. Drug Discovery|September 22, 2015
Tackling reproducibility in academic preclinical drug discoveryStephen V Frye, Michelle R Arkin, Cheryl H Arrowsmith, et al.
Journal of Biomolecular Screening|December 17, 2009
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteinsTim J Wigle, J Martin Herold, Guillermo A Senisterra, et al.
Plos One|June 22, 2017
Retraction: A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase InhibitorsBrandi M Baughman, Huanchen Wang, Yi An, et al.
ACS Chemical Biology|June 30, 2016
Chromodomain Ligand Optimization via Target-Class Directed Combinatorial RepurposingKimberly D Barnash, Kelsey N Lamb, Jacob I Stuckey, et al.
Journal of Medicinal Chemistry|May 17, 2021
Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1)Isabelle A Engelberg, Jiuyang Liu, Jacqueline L Norris-Drouin, et al.
Journal of Medicinal Chemistry|August 1, 2012
Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonistsXin Chen, Maria F Sassano, Lianyou Zheng, et al.
Plos One|October 14, 2016
A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase InhibitorsBrandi M Baughman, Huanchen Wang, Yi An, et al.
Pageof 13