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Scientific Reports|March 31, 2019
Monocytes/Macrophages play a pathogenic role in IL-23 mediated psoriasis-like skin inflammationYibing Wang, Rebecca Edelmayer, Joe Wetter, et al.
Pain|April 5, 2002
Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitorMichael F Jarvis, Haixia Yu, Steve McGaraughty, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 3, 2008
(R)-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) blocks polymodal activation of transient receptor potential vanilloid 1 receptors in vitro and heat-evoked firing of spinal dorsal horn neurons in vivoCarol S Surowy, Torben R Neelands, Bruce R Bianchi, et al.
The Journal of Dermatology|July 17, 2023
Importance of PLD2 in an IL-23 driven psoriasiform dermatitis model and potential link to human psoriasisZhi Su, Peter Slivka, Stephanie Paulsboe, et al.
Experimental Dermatology|November 13, 2018
IL-36 receptor antagonistic antibodies inhibit inflammatory responses in preclinical models of psoriasiform dermatitisZhi Su, Stephanie Paulsboe, Joseph Wetter, et al.
Journal of the American Society of Nephrology : JASN|August 23, 2017
Targeting Anti-TGF-β Therapy to Fibrotic Kidneys with a Dual Specificity Antibody ApproachSteve McGaraughty, Rachel A Davis-Taber, Chang Z Zhu, et al.
Bioorganic & Medicinal Chemistry Letters|August 28, 2003
Adenosine kinase inhibitors: polar 7-substitutent of pyridopyrimidine derivatives improving their locomotor selectivityGuo Zhu Zheng, Yue Mao, Chih-Hung Lee, et al.
Bioorganic & Medicinal Chemistry|January 2, 2007
4-amino-5-aryl-6-arylethynylpyrimidines: structure-activity relationships of non-nucleoside adenosine kinase inhibitorsMark A Matulenko, Ernest S Paight, Robin R Frey, et al.
Proceedings of the National Academy of Sciences of the United States of America|December 17, 2002
A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the ratMichael F Jarvis, Edward C Burgard, Steve McGaraughty, et al.
Bioorganic & Medicinal Chemistry|April 18, 2022
Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Nav1.7/ Nav1.8 blockers for the treatment of painMeena V Patel, Hillary M Peltier, Mark A Matulenko, et al.
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