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Journal of Medicinal Chemistry|December 22, 2010
Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activityMi-Yeon Jang, Yuan Lin, Steven De Jonghe, et al.Bioorganic & Medicinal Chemistry Letters|December 7, 2010
Synthesis and in vitro evaluation of 2-amino-4-N-piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agentsSteven De Jonghe, Arnaud Marchand, Ling-Jie Gao, et al.Antiviral Research|June 29, 2021
A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agentsThuc Nguyen Dan Do, Kim Donckers, Laura Vangeel, et al.The Journal of Organic Chemistry|February 22, 2002
Synthesis of homoceramides, novel ceramide analogues, and their lack of effect on the growth of hippocampal neuronsSteven De Jonghe, Inge Lamote, Krishnan Venkataraman, et al.Pharmaceuticals (Basel, Switzerland)|September 27, 2025
Structure-Activity Relationship Study of 3-Alkynyl-6-aryl-isothiazolo[4,3-<i>b</i>]pyridines as Dual Inhibitors of the Lipid Kinases PIKfyve and PIP4K2CDemian Kalebic, Ling-Jie Gao, Belén Martinez-Gualda, et al.European Journal of Medicinal Chemistry|June 16, 2026
Discovery of 1-(3-phenoxybenzyl)-4-(1-phenyl-1H-1,2,3-triazol-4-yl)piperidine analogues as potent and selective agonists of the human CC chemokine receptor 8Qifei Li, Wout Van Eynde, Tom Van Loy, et al.Journal of Medicinal Chemistry|November 16, 2020
Scalable Synthesis, In Vitro cccDNA Reduction, and In Vivo Antihepatitis B Virus Activity of a Phosphonomethoxydeoxythreosyl Adenine ProdrugMin Luo, Shuo Wu, Raj Kalkeri, et al.European Journal of Medicinal Chemistry|May 7, 2021
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptorsMaria Chiara Pismataro, Tommaso Felicetti, Chiara Bertagnin, et al.Journal of Medicinal Chemistry|June 29, 2018
Optimization of Isothiazolo[4,3- b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral ActivitySzu-Yuan Pu, Randy Wouters, Stanford Schor, et al.Frontiers in Chemistry|November 17, 2022
Synthesis and evaluation of 3-alkynyl-5-aryl-7-aza-indoles as broad-spectrum antiviral agentsBelén Martinez-Gualda, Mirthe Graus, Anita Camps, et al.Pageof 15