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ACS Medicinal Chemistry Letters|January 14, 2026
First-in-Class Potent, Dual HDAC6/Proteasome Inhibitors Lacking a Hydroxamic Acid Motif: Discovery of Novel Anti-Multiple Myeloma AgentsAlexandria M Chan, Brandon D Lowe, Andrea L Cottingham, et al.Cancer Research|July 3, 2004
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing AktLin Yang, Han C Dan, Mei Sun, et al.Cancer Research|May 20, 2004
Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptorJiazhi Sun, Michelle A Blaskovich, Rishi K Jain, et al.Blood|February 25, 2005
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cellsKuichun Zhu, Elvira Gerbino, Darrin M Beaupre, et al.Antimicrobial Agents and Chemotherapy|November 11, 2009
A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitroYao Cheng, Lun K Tsou, Jianfeng Cai, et al.BMC Cancer|November 23, 2012
The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibitionChander Peddaboina, Daniel Jupiter, Steven Fletcher, et al.Bioorganic & Medicinal Chemistry Letters|April 30, 2018
Kröhnke pyridines: Rapid and facile access to Mcl-1 inhibitorsIvie L Conlon, Daniel Van Eker, Sameh Abdelmalak, et al.Biodiversity Data Journal|August 3, 2017
A global map of saltmarshesChris J Mcowen, Lauren V Weatherdon, Jan-Willem Van Bochove, et al.Bioorganic & Medicinal Chemistry Letters|January 14, 2018
Discovery of Mcl-1 inhibitors based on a thiazolidine-2,4-dione scaffoldEllis Whiting, Mithun R Raje, Jay Chauhan, et al.Organic & Biomolecular Chemistry|February 1, 2006
Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferaseJunko Ohkanda, Corey L Strickland, Michelle A Blaskovich, et al.Pageof 26